Mimics of Pincer Ligands: An Accessible Phosphine-Free N-(Pyrimidin-2-yl)-1,2-azole-3-carboxamide Framework for Binuclear Pd(II) Complexes and High-Turnover Catalysis in Water

被引：22

作者：

Kletskov, Alexey, V ^{[1
,2
,3
,4
]}

Bumagin, Nikolay A. ^{[1
]}

Petkevich, Sergey K. ^{[2
]}

Dikusar, Evgenij A. ^{[2
]}

Lyakhov, Alexander S. ^{[5
]}

Ivashkevich, Ludmila S. ^{[5
]}

Kolesnik, Iryna A. ^{[2
]}

Potkin, Vladimir, I ^{[2
]}

机构：

[1] Moscow MV Lomonosov State Univ, Chem Dept, Moscow 119991, Russia

[2] Natl Acad Sci Belarus, Inst Phys Organ Chem, Minsk 220072, BELARUS

[3] Natl Acad Sci Belarus, Minsk 220072, BELARUS

[4] Peoples Friendship Univ Russia RUDN Univ, Moscow 117198, Russia

[5] Belarusian State Univ, Res Inst Phys Chem Problems, Minsk 220006, BELARUS

来源：

INORGANIC CHEMISTRY | 2020年 / 59卷 / 15期

基金：

俄罗斯基础研究基金会;

关键词：

CROSS-COUPLING REACTIONS; FUNCTIONALIZED NITROGEN LIGANDS; SUZUKI-MIYAURA REACTION; ORGANOBORON COMPOUNDS; ACID-DERIVATIVES; PALLADIUM; ISOTHIAZOLE; CHEMISTRY; ISOXAZOLE;

D O I：

10.1021/acs.inorgchem.0c01035

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We report for the first time cyclic phosphine-free "head to tail" N,N,N pincer-like (pincer complexes mimicking) N-(pyrimidin-2-yl)-1,2-azole-3-carboxamide Pd(II) complexes with deprotonated amide groups as high-turnover catalysts (TON up to 10(6), TOF up to 1.2 x 10(7) h(-1)) for cross-coupling reactions on the background of up to quantitative yields under Green Chemistry conditions. The potency of the described catalyst family representatives was demonstrated in Suzuki-Miyaura, Mizoroki-Heck, and Sonogashira reactions on industrially practical examples. Corresponding ligands could be synthesized based on readily available reagents through simple chemical transformations. Within the complex structures, a highly unusual 1,3,5,7-tetraza-2,6-dipalladocane frame could be observed.

引用

页码：10384 / 10388

页数：5

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