Enzyme-free strip biosensor for amplified detection of Pb2+ based on a catalytic DNA circuit

被引:70
|
作者
Chen, Junhua [1 ]
Zhou, Xuemeng [1 ]
Zeng, Lingwen [1 ]
机构
[1] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, S China Inst Stem Cell Biol & Regenerat Med, Key Lab Regenerat Biol, Guangzhou 510530, Guangdong, Peoples R China
关键词
LATERAL FLOW BIOSENSOR; GOLD NANOPARTICLES; ELECTROCHEMICAL DETECTION; NUCLEIC-ACIDS; DIPSTICK TEST; LEAD; AMPLIFICATION; DNAZYMES; PROBES;
D O I
10.1039/c2cc37598b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple and enzyme-free strip biosensor for the amplified detection of Pb2+ has been constructed based on a catalytic DNA circuit. This assay is ultrasensitive, enabling the visual detection of Pb2+ concentrations as low as 10 pM without instrumentation.
引用
收藏
页码:984 / 986
页数:3
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