Comparison of solid-phase sorbents for the determination of fluoroquinolone antibiotics in wastewater

被引：13

作者：

Zorita, Saioa ^{[1
]}

Larsson, Lennart ^{[2
]}

Mathiasson, Lennart ^{[1
]}

机构：

[1] Lund Univ, Div Analyt Chem, SE-22100 Lund, Sweden

[2] Lund Univ, Div Med Microbiol, SE-22100 Lund, Sweden

来源：

JOURNAL OF SEPARATION SCIENCE | 2008年 / 31卷 / 16-17期

关键词：

Fluoroquinolone antibiotics; LC-MS/MS; Matrix effect; Solid-phase extraction; Sorbent comparison;

D O I：

10.1002/jssc.200800301

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Three different SPE Sorbents (weak cation exchange, mixed cation exchange, and hydrophobic - lipophilic balance polymers)were compared in terms of recovery, precision, and the effect of matrix components on analyte response for the determination of fluoroquinolones antibiotics. The influence of ethylenediaminetetraacetic acid disodium salt (Na-2-EDTA) was as well tested. Two of the sorbents, hydrophilic-lipophilic balance (HLB) and weak cation exchange (WCX), turned out to be suitable for ultratrace analysis. HLB sorbent showed higher capacity for analyte trapping and better precision while weak cation exchange sorbent had a superior performance in terms of selectivity. In complex samples, the higher capacity of HLB was outweighed by the higher selectivity of WCX when considering the LODs of the methods.

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收藏

页码：3117 / 3121

页数：5

相关论文

共 14 条

[1] Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment [J].

Andreozzi, R ;

Marotta, R ;

Paxeus, N .

CHEMOSPHERE, 2003, 50 (10) :1319-1330

[2] Occurrence of antibiotics in hospital, residential, and dairy, effluent, municipal wastewater, and the Rio Grande in New Mexico [J].

Brown, Kathryn D. ;

Kulis, Jerzy ;

Thomson, Bruce ;

Chapman, Timothy H. ;

Mawhinney, Douglas B. .

SCIENCE OF THE TOTAL ENVIRONMENT, 2006, 366 (2-3) :772-783

[3] Trace determination of fluoroquinolone antibacterial agents in solid-phase extraction urban wastewater by and liquid chromatography with fluorescence detection [J].

Golet, EM ;

Alder, AC ;

Hartmann, A ;

Ternes, TA ;

Giger, W .

ANALYTICAL CHEMISTRY, 2001, 73 (15) :3632-3638

[4] Determination of pharmaceuticals of various therapeutic classes by solid-phase extraction and liquid chromatography-tandem mass spectrometry analysis in hospital effluent wastewaters [J].

Gomez, M. Jose ;

Petrovic, Mira ;

Fernandez-Alba, Amadeo R. ;

Barcelo, Damia .

JOURNAL OF CHROMATOGRAPHY A, 2006, 1114 (02) :224-233

[5] Determination of antibiotics in different water compartments via liquid chromatography electrospray tandem mass spectrometry [J].

Hirsch, R ;

Ternes, TA ;

Haberer, K ;

Mehlich, A ;

Ballwanz, F ;

Kratz, KL .

JOURNAL OF CHROMATOGRAPHY A, 1998, 815 (02) :213-223

[6] Toxic and genotoxic evaluation of six antibiotics on non-target organisms [J].

Isidori, M ;

Lavorgna, M ;

Nardelli, A ;

Pascarella, L ;

Parrella, A .

SCIENCE OF THE TOTAL ENVIRONMENT, 2005, 346 (1-3) :87-98

[7] Occurrence of antibiotics in wastewater treatment facilities in Wisconsin, USA [J].

Karthikeyan, KG ;

Meyer, MT .

SCIENCE OF THE TOTAL ENVIRONMENT, 2006, 361 (1-3) :196-207

[8] Determination of ofloxacin, norfloxacin, and ciprofloxacin in sewage by selective solid-phase extraction, liquid chromatography with fluorescence detection, and liquid chromatography-tandem mass spectrometry [J].

Lee, Hing-Biu ;

Peart, Thomas E. ;

Svoboda, M. Lewina .

JOURNAL OF CHROMATOGRAPHY A, 2007, 1139 (01) :45-52

[9] Occurrence of antimicrobials in the final effluents of wastewater treatment plants in Canada [J].

Miao, XS ;

Bishay, F ;

Chen, M ;

Metcalfe, CD .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2004, 38 (13) :3533-3541

[10] Determination of fluoroquinolone antibiotics in wastewater effluents by liquid chromatography-mass spectrometry and fluorescence detection [J].

Nakata, H ;

Kannan, K ;

Jones, PD ;

Giesy, JP .

CHEMOSPHERE, 2005, 58 (06) :759-766