Molecular insights into the physiology of the 'thin film' of airway surface liquid

被引:135
作者
Boucher, RC [1 ]
机构
[1] Univ N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Chapel Hill, NC 27599 USA
来源
JOURNAL OF PHYSIOLOGY-LONDON | 1999年 / 516卷 / 03期
关键词
D O I
10.1111/j.1469-7793.1999.0631u.x
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The epithelia that line the airways of the lung exhibit two general functions: (1) airway epithelia in all regions 'defend' the lung against infectious and noxious agents; and (2) airway epithelia in the proximal regions replenish water lost from airway surfaces, i.e. the 'insensible water loss', consequent to conditioning inspired air. How airway epithelia perform both functions, and co-ordinate them in health and disease, is the subject of this review.
引用
收藏
页码:631 / 638
页数:8
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