Novel biomarkers predicting cardiac function after acute myocardial infarction

被引:25
作者
Feistritzer, Hans-Josef [1 ]
Klug, Gert [1 ]
Reinstadler, Sebastian J. [1 ]
Reindl, Martin [1 ]
Mayr, Agnes [2 ]
Mair, Johannes [1 ]
Metzler, Bernhard [1 ]
机构
[1] Med Univ Innsbruck, Univ Clin Internal Med 3, Dept Cardiol & Angiol, Anichstr 35, A-6020 Innsbruck, Austria
[2] Med Univ Innsbruck, Dept Radiol, Anichstr 35, A-6020 Innsbruck, Austria
关键词
biomarkers; acute myocardial infarction; cardiac function; prognosis; LEFT-VENTRICULAR FUNCTION; TERMINAL PROVASOPRESSIN COPEPTIN; ISCHEMIA-REPERFUSION INJURY; BRAIN NATRIURETIC PEPTIDE; CORONARY-ARTERY-DISEASE; SENSITIVITY TROPONIN-T; ALL-CAUSE MORTALITY; HEART-FAILURE; INDEPENDENT PREDICTOR; RISK STRATIFICATION;
D O I
10.1093/bmb/ldw027
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Measurement of biomarkers provides a cost-effective and widely available method to estimate cardiac dysfunction and clinical outcome of patients with acute myocardial infarction (AMI). PubMed entries with terms 'myocardial infarction' and the respective biomarker. Cardiac troponins and natriuretic peptides are closely related to left ventricular dysfunction and the occurrence of adverse clinical events following AMI. The incremental value of novel biomarkers is controversial. The combination of traditional and novel biomarkers might further improve risk stratification of patients with AMI. We searched all entries on the PubMed database with the MeSH terms 'myocardial infarction' and 'cardiac troponins', 'natriuretic peptides', 'copeptin', galectin-3', 'corin', 'fetuin-A', 'adiponectin' and 'microRNA'.
引用
收藏
页码:63 / 74
页数:12
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