Cerebellar granulocytic sarcoma in an infant with CD56+acute monoblastic leukemia

被引：20
作者：
Psiachou-Leonard, E
Paterakis, G
Stefanaki, K
Mikraki-Christou, V
Haidas, S
机构：
[1] Aghia Sophia Childrens Hosp, Dept Haematol Oncol, Athens 11527, Greece
[2] Gen Hosp G Gennimatas, Dept Immunol & Histocompatibil, Athens, Greece
[3] Aghia Sophia Childrens Hosp, Dept Pathol, Athens 11527, Greece
来源：
LEUKEMIA RESEARCH | 2001年 / 25卷 / 11期
关键词：
acute myeloid leukaemia; cerebellum; granulocytic sarcoma; NCAM;
D O I：
10.1016/S0145-2126(01)00068-6
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Granulocytic sarcoma (GS) is a form of extramedullary leukaemia (EML). The presence of the neural cell adhesion molecule (NCAM) on the surface of the blasts, which is recognized by the CD56 monoclonal antibody, enhances their propensity for tissue penetration. GS within the central nervous system (CNS), in particular within the cerebellum, is extremely uncommon. We review the literature and describe an infant with isolated cerebellar GS relapse, which antedated a CD56 + acute monoblastic leukaemia bone marrow (BM) relapse. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1019 / 1021
页数：3
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