Monthly measurements of indoor allergens and the influence of housing type in a northeastern US city

被引:84
作者
Chew, GL
Higgins, KM
Gold, DR
Muilenberg, ML
Burge, HA
机构
[1] Columbia Univ, Sch Publ Hlth, Div Environm Hlth Sci, New York, NY 10032 USA
[2] US FDA, Rockville, MD 20857 USA
[3] Harvard Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA 02115 USA
[4] Brigham & Womens Hosp, Channing Lab, Dept Med, Boston, MA 02115 USA
[5] Harvard Univ, Sch Med, Boston, MA USA
关键词
allergens; cat; cockroach; dust mite; seasonal variation;
D O I
10.1034/j.1398-9995.1999.00003.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background: We examined seasonal variation of dust-mile (Der f 1 and Der p 1), cat (Fel d 1), and cockroach (Bla g 1) allergens in Boston, while adjusting for other covariates. Limited data are available on seasonal patterns of indoor allergen concentrations for different geographic regions in the USA. Understanding within-home seasonal variation of allergens is important epidemiologically and clinically. Methods: From June 1995 to June 1996, dust samples were vacuumed monthly from the bed, bedroom floor; and kitchen of 20 homes. Indoor temperatures were measured monthly and used in calculating relative and absolute humidity. Monthly home characteristics questionnaires were completed by an adult resident of each home. Dust samples were assayed by enzyme-linked immunosorbent assays. Results: Der f I and Der p 1 in beds and floors peaked in the autumn months, Fel d 1 peaked in winter and spring, and Bla g 1 was highest in summer. Dust-mite allergen concentrations were 1.9-2.4 times higher in autumn than spring, but the levels in beds were 19-31 times higher in houses than those in apartments. Although Fel d 1 levels in beds were 2.4 times higher in spring than summer, homes with cats had levels 224 times higher than those without cats. Similarly, Bla g 1 levels in kitchens were 2.1 times higher in summer than winter, but apartments had, levels five times higher than those of houses. Conclusions: Sampling season is a source of within-home dust-mite, fat, and cockroach allergen variation in-the northeastern USA. However, the influence of housing type and owning a cat far outweighed the seasonal Variation of these indoor allergens.
引用
收藏
页码:1058 / 1066
页数:9
相关论文
共 25 条
[1]   RE-EVALUATION OF THE HUMIDITY REQUIREMENTS OF THE HOUSE DUST MITE DERMATOPHAGOIDES-FARINAE (ACARI, PYROGLYPHIDAE) [J].
ARLIAN, LG ;
VESELICA, MM .
JOURNAL OF MEDICAL ENTOMOLOGY, 1981, 18 (04) :351-352
[2]   DEHYDRATION AND SURVIVAL OF EUROPEAN HOUSE DUST MITE, DERMATOPHAGOIDES-PTERONYSSINUS [J].
ARLIAN, LG .
JOURNAL OF MEDICAL ENTOMOLOGY, 1975, 12 (04) :437-442
[3]   MORTALITY OF HOUSE DUST MITES, DERMATOPHAGOIDES-FARINAE AND D.-PTERONYSSINUS, EXPOSED TO DEHYDRATING CONDITIONS OR SELECTED PESTICIDES [J].
BRANDT, RL ;
ARLIAN, LG .
JOURNAL OF MEDICAL ENTOMOLOGY, 1976, 13 (03) :327-331
[4]  
CHAPMAN MD, 1988, J IMMUNOL, V140, P812
[5]   AIRBORNE CAT ALLERGEN (FEL-D-I) - ENVIRONMENTAL-CONTROL WITH THE CAT INSITU [J].
DEBLAY, F ;
CHAPMAN, MD ;
PLATTSMILLS, TAE .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1991, 143 (06) :1334-1339
[6]   SENSITIZATION AND EXPOSURE TO INDOOR ALLERGENS AS RISK-FACTORS FOR ASTHMA AMONG PATIENTS PRESENTING TO HOSPITAL [J].
GELBER, LE ;
SELTZER, LH ;
BOUZOUKIS, JK ;
POLLART, SM ;
CHAPMAN, MD ;
PLATTSMILLS, TAE .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1993, 147 (03) :573-578
[7]   HOUSE-DUST MITES AND ASSOCIATED ENVIRONMENTAL-CONDITIONS IN DANISH HOMES [J].
HARVING, H ;
KORSGAARD, J ;
DAHL, R .
ALLERGY, 1993, 48 (02) :106-109
[8]   QUANTITATIVE ASSESSMENT OF EXPOSURE TO DOG (CAN-F-1) AND CAT (FEL-D-1) ALLERGENS - RELATION TO SENSITIZATION AND ASTHMA AMONG CHILDREN LIVING IN LOS-ALAMOS, NEW-MEXICO [J].
INGRAM, JM ;
SPORIK, R ;
ROSE, G ;
HONSINGER, R ;
CHAPMAN, MD ;
PLATTSMILLS, TAE .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1995, 96 (04) :449-456
[9]   MITE ASTHMA IN CHILDHOOD - A STUDY OF THE RELATIONSHIP BETWEEN EXPOSURE TO HOUSE DUST MITES AND DISEASE-ACTIVITY [J].
KIVITY, S ;
SOLOMON, A ;
SOFERMAN, R ;
SCHWARZ, Y ;
MUMCUOGLU, KY ;
TOPILSKY, M .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1993, 91 (04) :844-849
[10]   RANDOM-EFFECTS MODELS FOR LONGITUDINAL DATA [J].
LAIRD, NM ;
WARE, JH .
BIOMETRICS, 1982, 38 (04) :963-974