Semicomprehensive and semiquantitative determination of proteins with mass probes

被引：5

作者：

Honda, A

Hifumi, H

Honma, Y

Tanji, N

Suzuki, Y

Suzuki, K

机构：

[1] Keio Univ, Dept Appl Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

[2] Japan Sci & Technol Agcy, CREST, Kawaguchia 3320012, Japan

[3] Kanagawa Acad Sci & Technol, CITY AREA, Takatsu Ku, Kawasaki, Kanagawa 2130012, Japan

来源：

CHEMISTRY LETTERS | 2006年 / 35卷 / 03期

关键词：

D O I：

10.1246/cl.2006.290

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have designed and synthesized a series of mass-probes, which could be a model of a new tool for the semicomprehensive quantitative assays of proteins using mass spectrometry. In the system with mass-probes, the molecular weights were used as markers. We have synthesized the two probes, KMP-174 and KNIP-188, and ovalbumin (OVA) and the hen egg lysozyme (HEL) were evaluated by antibodies labeled with those probes.

引用

收藏

页码：290 / 291

页数：2

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