Psoriasis and Co-morbidities

Psoriasis is a chronic inflammatory skin disorder affecting about 1-3% of general population, is defined among Immune Mediated Inflammatory Disease (IMID) since it develops with immune associated mechanisms. it has been proposed that the chronic inflammation in psoriasis have role in the development of metabolic and vascular disorders related with psoriasis and recent studies have focused on the psoriasis associating comorbidities and their mechanisms. Psoriasis comorbidities include psoriatic arthritis, Crohn's disease, pustular disorders, metabolic syndrome, malignities, comorbidities related to treatments, pulmonary diseases, smoking, infections, impact on life quality and depression, and alcohol. (Turkderm 2008; 42 Suppl 2: 23-5)