Treatment of bone and soft tissue sarcomas of the hand and wrist

被引:11
作者
Kawai, A [1 ]
Hasizume, H [1 ]
Sugihara, S [1 ]
Morimoto, Y [1 ]
Inoue, H [1 ]
机构
[1] Okayama Univ, Sch Med, Dept Orthopaed Surg, Okayama 7008558, Japan
关键词
D O I
10.1007/s002640100297
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
We studied 13 consecutive patient with bone and soft tissue sarcomas of the hand and wrist. Chondrosarcoma. Ewing's sarcoma, synovial sarcoma and epithelioid sarcoma were the most frequent histological diagnoses. Limb-sparing surgery was performed in tell patients but eventually three patients required all amputation. Surgical margins were wide in nine patients and marginal in four. Adjuvant therapy for nine patients consisted of chemotherapy in five and chemotherapy with radiation in four. Local recurrence occurred in two patients with epithelioid sarcoma. There was no significant relationship between surgical mar-in and local recurrence. Distant metastasis occurred in four patients. The 5-year survival rate was 66%. The mean functional score Was 87%. Our study indicates that treatment consisting, of resection of these tumours with either a wide margins or a marginal margin followed by adjuvant radiation appeared to be safe and resulted in an acceptable degree of limb function except in the patients with epithelioid sarcoma.
引用
收藏
页码:26 / 30
页数:5
相关论文
共 30 条
[1]   Limb salvage surgery and adjuvant radiotherapy for soft tissue sarcomas of the forearm and hand [J].
Bray, PW ;
Bell, RS ;
Bowen, CVA ;
Davis, A ;
OSullivan, B .
JOURNAL OF HAND SURGERY-AMERICAN VOLUME, 1997, 22A (03) :495-503
[2]   TREATMENT OF SOFT-TISSUE SARCOMAS OF THE HAND [J].
BRIEN, EW ;
TEREK, RM ;
GEER, RJ ;
CALDWELL, G ;
BRENNAN, MF ;
HEALEY, JH .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1995, 77A (04) :564-571
[3]   PRIMARY EPITHELIOID SARCOMA OF HAND AND FOREARM REVIEW OF 13 CASES [J].
BRYAN, RS ;
SOULE, EH ;
DOBYNS, JH ;
PRITCHARD, DJ ;
LINSCHEID, RL .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1974, A 56 (03) :458-465
[4]  
Campanacci M, 1981, Ital J Orthop Traumatol, V7, P313
[5]   RESPONSE TO MESNA, DOXORUBICIN, IFOSFAMIDE, AND DACARBAZINE IN 108 PATIENTS WITH METASTATIC OR UNRESECTABLE SARCOMA AND NO PRIOR CHEMOTHERAPY [J].
ELIAS, A ;
RYAN, L ;
SULKES, A ;
COLLINS, J ;
AISNER, J ;
ANTMAN, KH .
JOURNAL OF CLINICAL ONCOLOGY, 1989, 7 (09) :1208-1216
[6]  
ENNEKING WF, 1993, CLIN ORTHOP RELAT R, P241
[7]  
Enzinger F., 1995, SOFT TISSUE TUMOURS, P838
[8]  
ENZINGER FM, 1970, CANCER-AM CANCER SOC, V26, P1029, DOI 10.1002/1097-0142(197011)26:5<1029::AID-CNCR2820260510>3.0.CO
[9]  
2-R
[10]  
GOORIN A, 1998, SURG BONE SOFT TISSU