Insights into the role of adipose-derived stem cells: Wound healing and clinical regenerative potential

被引:17
作者
Zou, Ming-Li [1 ,2 ]
Liu, Si-Yu [1 ,2 ]
Sun, Zi-Li [1 ,2 ]
Wu, Jun-Jie [2 ]
Yuan, Zheng-Dong [2 ]
Teng, Ying-Ying [2 ]
Feng, Yi [2 ,3 ]
Yuan, Feng-Lai [1 ,2 ,4 ]
机构
[1] Nanjing Univ Chinese Med, Sch Integrated Chinese & Western Med, Wuxi Clin Med, Wuxi, Jiangsu, Peoples R China
[2] Jiangnan Univ, Dept Burns & Plast Surg, Affiliated Hosp, Wuxi 214041, Jiangsu, Peoples R China
[3] Yangzhou Univ, Med Sch, Dept Pharmacol, Yangzhou, Jiangsu, Peoples R China
[4] Nantong Univ, Dept Cent Lab, Hosp 3, Wuxi, Jiangsu, Peoples R China
关键词
adipose-derived stem cells; fat grafting; regenerative; tissue repair; wound healing; TISSUE; DIFFERENTIATION; ANGIOGENESIS; EXPRESSION; EXOSOMES; THERAPY;
D O I
10.1002/jcp.30019
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The incidence of acute and chronic wound diseases is rising due to various reasons. With complicated pathogenesis, long course, difficult treatment and high disability, wound diseases have become a major burden for patients, their families, and society. Therefore, the focus of research is to identify new ideas and methods for treatment. Fat grafting has gained increased attention because of its effectiveness in wound treatment, and further analysis has uncovered that the stem cells derived from fat may be the main factor affecting wound healing. We summarize the function of adipose stem cells and analyze their possible mechanisms in tissue repair, helping to provide new ideas for the treatment of wound healing.
引用
收藏
页码:2290 / 2297
页数:8
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