Infection-Induced Systemic Inflammation Is a Potential Driver of Alzheimer's Disease Progression

被引：53
作者：
Giridharan, Vijayasree V. [1 ]
Masud, Faisal [2 ]
Petronilho, Fabricia [3 ]
Dal-Pizzol, Felipe [4 ]
Barichello, Tatiana [1 ,4 ,5 ]
机构：
[1] Univ Texas Hlth Sci Ctr Houston, Dept Psychiat & Behav Sci, Translat Psychiat Program, McGovern Med Sch, Houston, TX 77030 USA
[2] Houston Methodist Hosp, Dept Anesthesiol, Houston, TX USA
[3] Univ South Santa Catarina, Hlth Sci Unit, Lab Neurobiol Inflammatory & Metab Proc, Grad Program Hlth Sci, Tubarao, Brazil
[4] Univ Southern Santa Catarina, Lab Expt Pathophysiol, Grad Program Hlth Sci, Criciuma, Brazil
[5] Univ Southern Santa Catarina UNESC, Grad Program Hlth Sci, Lab Neurosci, Criciuma, Brazil
来源：
FRONTIERS IN AGING NEUROSCIENCE | 2019年 / 11卷
关键词：
infection; systemic inflammation; neuroinflammation; Alzheimer's disease; cognition; AMYLOID-BETA; MICROGLIA; INHIBITION; PNEUMONIAE; ETIOLOGY; SEPSIS;
D O I：
10.3389/fnagi.2019.00122
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
[No abstract available]
引用
收藏
页数：5
相关论文
共 47 条
  • [1] Association between Periodontitis and Alzheimer's Disease
    Abbayya, Keshava
    Puthanakar, Nagraj Y.
    Naduwinmani, Sanjay
    Chidambar, Y. S.
    [J]. NORTH AMERICAN JOURNAL OF MEDICAL SCIENCES, 2015, 7 (06) : 241 - 246
  • [2] Mechanisms of Blood Brain Barrier Disruption by Different Types of Bacteria, and Bacterial-Host Interactions Facilitate the Bacterial Pathogen Invading the Brain
    Al-Obaidi, Mazen M. Jamil
    Desa, Mohd Nasir Mohd
    [J]. CELLULAR AND MOLECULAR NEUROBIOLOGY, 2018, 38 (07) : 1349 - 1368
  • [3] The Possibility of an Infectious Etiology of Alzheimer Disease
    Ashraf, Ghulam M.
    Tarasov, Vadim V.
    Makhmutova, Alfiya
    Chubarev, Vladimir N.
    Avila-Rodriguez, Marco
    Bachurin, Sergey O.
    Aliev, Gjumrakch
    [J]. MOLECULAR NEUROBIOLOGY, 2019, 56 (06) : 4479 - 4491
  • [4] Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease
    Baker, Sarah K.
    Chen, Zu-Lin
    Norris, Erin H.
    Revenko, Alexey S.
    MacLeod, A. Robert
    Strickland, Sidney
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (41) : E9687 - E9696
  • [5] Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain
    Balin, BJ
    Gerard, HC
    Arking, EJ
    Appelt, DM
    Branigan, PJ
    Abrams, JT
    Whittum-Hudson, JA
    Hudson, AP
    [J]. MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 1998, 187 (01) : 23 - 42
  • [6] Balin BJ, 2008, J ALZHEIMERS DIS, V13, P371
  • [7] A study on the association between infectious burden and Alzheimer's disease
    Bu, X. -L.
    Yao, X. -Q.
    Jiao, S. -S.
    Zeng, F.
    Liu, Y. -H.
    Xiang, Y.
    Liang, C. -R.
    Wang, Q. -H.
    Wang, X.
    Cao, H. -Y.
    Yi, X.
    Deng, B.
    Liu, C. -H.
    Xu, J.
    Zhang, L. -L.
    Gao, C. -Y.
    Xu, Z. -Q.
    Zhang, M.
    Wang, L.
    Tan, X. -L.
    Xu, X.
    Zhou, H. -D.
    Wang, Y. -J.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2015, 22 (12) : 1519 - 1525
  • [8] Virus entry and replication in the brain precedes blood-brain barrier disruption during intranasal alphavirus infection
    Cain, Matthew D.
    Salimi, Hamid
    Gong, Yongfeng
    Yang, Lihua
    Hamilton, Samantha L.
    Heffernan, James R.
    Hou, Jianghui
    Miller, Mark J.
    Klein, Robyn S.
    [J]. JOURNAL OF NEUROIMMUNOLOGY, 2017, 308 : 118 - 130
  • [9] Peripheral immune system in aging and Alzheimer's disease
    Cao, Wei
    Zheng, Hui
    [J]. MOLECULAR NEURODEGENERATION, 2018, 13
  • [10] Amyloid beta: structure, biology and structure-based therapeutic development
    Chen, Guo-fang
    Xu, Ting-hai
    Yan, Yan
    Zhou, Yu-ren
    Jiang, Yi
    Melcher, Karsten
    Xu, H. Eric
    [J]. ACTA PHARMACOLOGICA SINICA, 2017, 38 (09) : 1205 - 1235
12345