Low-grade Myofibroblastic sarcoma: clinical and imaging findings

被引:29
作者
Wang, Lu [1 ]
Li, Ling-Xia [2 ]
Chen, De-Qiang [3 ]
Yang, Lin [3 ]
Li, Shu-Kui [1 ]
Cheng, Cai [1 ]
机构
[1] Cang Zhou Cent Hosp, Dept Orthoped, Cang Zhou 061014, Peoples R China
[2] Cang Zhou Peoples Hosp, Dept Clin Pharmacol, Cang Zhou 061000, Peoples R China
[3] Cang Zhou Cent Hosp, Dept Radiol, Cang Zhou 061014, Peoples R China
关键词
Low-grade myofibroblastic sarcoma (LGMS); Bones; Soft tissues; CT; MRI; TUMOR;
D O I
10.1186/s12880-018-0287-z
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
BackgroundLow-grade myofibroblastic sarcoma (LGMS) is a rare type of tumor. Previous research has paid much attention to reporting pathological analyses of LGMS. However, only few systematic clinical and/or radiological studies have been conducted.MethodsThis study recruited 14 cases (8 males and 6 females) of LGMS. X-ray or computer tomography (CT) scan were performed on 11 cases. MRI was performed on 5 cases.ResultsX-Ray and CT scan: Five cases developed LGMS in bones, including 3 cases in the distal femur, 1 in the right shoulder blade, and another 1 in the right inferior ramus. Massive infiltrative and vermiform bone destruction with poorly-circumscribed lesion margins and partial soft tissue masses were observed. The other 9 cases were developed in soft tissues. Out of them, 4 cases presented slightly irregular hyper- or lower-density masses with poorly-circumscribed margins. 2 cases presented massive calcification and ossification. Significant enhancement was observed in 1 case, while no obvious enhancement was seen in the other 2 cases.MRI: MR images of 5 cases revealed homogeneous iso- or hyper-signal intensity on T1WI and homogeneous or heterogeneous hyper-signal intensity on T2WI. Enhanced MRI revealed homogeneous enhancement in 2 cases and rim enhancement in 1 case.ConclusionsOur findings show that LGMS is characterized by invasiveness, metastases and calcification. Different radiological tools should be employed to make an accurate diagnosis.
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页数:9
相关论文
共 13 条
[1]   Low-grade myofibroblastic sarcoma of the piriform fossa: A case report with a literature review of a tumour with a predilection for the head and neck [J].
Coyne, J. D. .
BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 2007, 45 (04) :335-337
[2]   Myofibrosarcoma [J].
Fisher, C .
VIRCHOWS ARCHIV, 2004, 445 (03) :215-223
[3]  
Fletcher CDM, 2013, CLASSIFICATION TUMOU, P327
[4]  
Gocht A, 1999, PATHOL RES PRACT, V195, P1
[5]   Breast sarcoma showing myofibroblastic differentiation [J].
Lucin, K ;
Mustac, E ;
Jonjic, N .
VIRCHOWS ARCHIV, 2003, 443 (02) :222-224
[6]   Low-grade myofibroblastic sarcoma - Analysis of 18 cases in the spectrum of myofibroblastic tumors [J].
Mentzel, T ;
Dry, S ;
Katenkamp, D ;
Fletcher, CDM .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1998, 22 (10) :1228-1238
[7]  
Miyazawa M, 2011, ANTICANCER RES, V31, P2989
[8]   Myofibrosarcoma - A clinicopathologic study [J].
Montgomery, E ;
Goldblum, JR ;
Fisher, C .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2001, 25 (02) :219-228
[9]   Uncommon malignancies - Case 1. Low-grade myofibroblastic sarcoma of the breast [J].
Morgan, PB ;
Chundru, S ;
Hatch, SS ;
Hawkins, HK ;
Adegboyega, PA ;
Eltorky, MA .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (25) :6249-6251
[10]   Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review [J].
Ni, C. ;
Xu, Y-Y ;
Zhou, S-H ;
Wang, S-Q .
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2011, 39 (01) :311-320