Macaque immune responses following AAV-based gene transfer to the skeletal muscle: addressing the method of vector delivery

被引：0

作者：

Gernoux, Gwladys ^{[1
]}

Devaux, Marie ^{[1
]}

Dubreil, Laurence ^{[2
]}

Jaulin, Nicolas ^{[1
]}

Guilbaud, Mickael ^{[1
]}

Deschamps, Jack-Yves ^{[2
]}

Larcher, Thibaut ^{[2
]}

Guigand, Lydie ^{[2
]}

Dutilleul, Maeva ^{[2
]}

Cherel, Yan ^{[2
]}

Moullier, Philippe ^{[1
,3
,4
]}

Adjali, Oumeya ^{[1
]}

机构：

[1] Inst Rech Therapeut, INSERM UMR1089, Nantes, France

[2] ONIRIS, INRA UMR703, Nantes, France

[3] Univ Florida, Dept Mol Genet, Gainesville, FL USA

[4] Univ Florida, Dept Microbiol, Gainesville, FL USA

来源：

HUMAN GENE THERAPY | 2012年 / 23卷 / 10期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：A130 / A130

页数：1

共 33 条

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BLOOD, 2015, 126 (23)
[22] Viral serotype and the transgene sequence influence overlapping adeno-associated viral (AAV) vector-mediated gene transfer in skeletal muscle
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[23] T Cell Responses to Canine Factor IX and AAV Capsid Antigens in Hemophilia B Dogs after Intravascular Gene Delivery to Skeletal Muscle
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Mingozzi, Federico
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Arruda, Valder R.
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[24] Major role of local antigen presentation in immune responses to factor IX in viral gene transfer to skeletal muscle.
Cao, O
Wang, LX
Swalm, B
Herzog, RW
BLOOD, 2003, 102 (11) : 743A - 743A
[25] Systemic protein delivery by rAAV-mediated gene transfer in nonhuman primate skeletal muscle is limited by a local immune response
Toromanoff, Alice
Cherel, Yan
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HUMAN GENE THERAPY, 2007, 18 (10) : 985 - 985
[26] Redundancy in Innate Immune Pathways That Promote CD8+ T-Cell Responses in AAV1 Muscle Gene Transfer
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Cao, Di
Munoz-Melero, Maite
Arisa, Sreevani
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[27] Effectiveness of Engineering AAV Vector Genomes to Evade TLR9 Signaling for Prevention of CD8+ T Cell Responses in Muscle Gene Transfer is Vector Dose Dependent
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Li, Ning
Herzog, Roland W.
MOLECULAR THERAPY, 2023, 31 (04) : 73 - 74
[28] Neutralising antibody responses to intravitreally delivered AAV2 and exosome-associated AAV2 vectors are associated with a failure of repeated gene transfer following vector readministration in the ipsilateral eye
Whitehead, Michael
Osborne, Andrew
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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2020, 61 (07)
[29] Oral-tolerization Prevents Immune Responses and Improves Transgene Persistence Following Gene Transfer Mediated by Adeno-associated Viral Vector
Hardet, Romain
Chevalier, Benjamin
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MOLECULAR THERAPY, 2016, 24 (01) : 87 - 95
[30] Delivery of α1-antitrypsin to the lung via adeno-associated virus vector-mediated gene transfer is more efficient by intrapleural delivery rather than skeletal muscle administration
De, BP
Merritt, R
Lam, M
Hackett, NR
Crystal, RG
MOLECULAR THERAPY, 2003, 7 (05) : S186 - S186

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