Optimal duration of cooling for an acute scald contact burn injury in a porcine model

被引:73
作者
Bartlett, Nita [3 ,4 ]
Yuan, Jennifer [3 ,4 ]
Holland, Andrew. J. A. [1 ,3 ,4 ]
Harvey, John G. [3 ,4 ]
Martin, Hugh C. O. [3 ,4 ]
La Hei, Erik R. [3 ,4 ]
Arbuckle, Susan [2 ]
Godfrey, Craig [3 ,4 ]
机构
[1] Univ Sydney, Childrens Hosp, Acad Dept Surg, Westmead, NSW 2145, Australia
[2] Univ Sydney, Childrens Hosp, Dept Histopathol, Westmead, NSW 2145, Australia
[3] Univ Sydney, Childrens Hosp, Burns Res Inst, Westmead, NSW, Australia
[4] Univ Sydney, Childrens Hosp, Burns Unit, Westmead, NSW, Australia
关键词
D O I
10.1097/BCR.0b013e3181855c9a
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The Australian and New Zealand Burn Association recommend 20 minutes of cold running tap water as burn first aid. Scientific evidence for the optimal duration of treatment is limited. Our aim was to establish the optimal duration of cooling using cold running tap water to treat the acute burn. Partial thickness contact scald burns were induced at five sites ill each of 17 pigs. Treatments with cold running tap water for 5, 10, 20, and 30 minutes were randomly allocated to different sites together with all untreated control site. In the running water 5 and 10 minute treatments intradermal temperatures rose by 1 degrees C per minute when cooling was stopped, compared with 0.5 degrees C per minute for 20 and 30 minutes duration. No differences in the surface area of each burn were noted between the five treatments oil day 9. Histological analysis of burn depth Oil days 1 and 9 revealed that a higher proportion of burns treated for 20 and 30 minutes showed improvement compared with those treated for 5 and 10 minutes only. This difference reached statistical significance (P < .05) only in the cold running water for 20 minutes treatment arm. There was a statistically significant (P < .05) improvement in burn depth in a porcine acute scald burn injury model when the burn was treated with cold running tap water for 20 minutes as opposed to the other treatment durations. This study supports the current burn first aid treatment recommendations for the optimal duration of cooling an acute scald burn.
引用
收藏
页码:828 / 834
页数:7
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