Analysis and role of oligosaccharides in milk

被引：44
作者：
Ruhaak, L. Renee [1 ]
Lebrilla, Carlito B. [1 ]
机构：
[1] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA
来源：
BMB REPORTS | 2012年 / 45卷 / 08期
基金：
美国国家卫生研究院;
关键词：
Analysis; Bacterial consumption; High performance liquid chromatography; Lewis blood group; Mass spectrometry; Milk oligosaccharides; Secretor status; BREAST-FED INFANTS; HYDROPHILIC INTERACTION CHROMATOGRAPHY; INFRARED MULTIPHOTON DISSOCIATION; NEGATIVE-ION MODE; MASS-SPECTROMETRY; CHEMICAL-CHARACTERIZATION; FUCOSYLATED OLIGOSACCHARIDES; LIQUID-CHROMATOGRAPHY; FED BABIES; BIFIDOBACTERIAL CONSUMPTION;
D O I：
10.5483/BMBRep.2012.45.8.161
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Milk is an important fluid in glycobiology because it contains a number of short carbohydrate chains either free or as glycoconjugates. These compounds as a class are the most abundant component and benefit the infant by developing and maintaining the infant's gut flora. New and emerging methods for oligosaccharide analysis have been developed to study milk. These methods allow for the rapid profiling of oligosaccharide mixtures with quantitation. With these tools, the role of oligosaccharide in milk is being understood. They further point to how oligosaccharide analysis can be performed, which until now has been very difficult and have lagged significantly those of other biopolymers. [BMB Reports 2012; 45(8): 442-451]
引用
收藏
页码：442 / 451
页数：10
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