Metastable hydrogels from aromatic dipeptides

被引：53

作者：

Conte, M. P. ^{[1
]}

Singh, N. ^{[2
]}

Sasselli, I. R. ^{[1
]}

Escuder, B. ^{[2
]}

Ulijn, R. V. ^{[1
,3
,4
,5
,6
]}

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, WestCHEM, 99 George St, Glasgow G1 1RD, Lanark, Scotland

[2] Univ Jaume 1, Dept Quim Inorgan & Organ, Castellon de La Plana 12071, Spain

[3] ASRC, 85 St Nicholas Terrace, New York, NY 10027 USA

[4] CUNY Hunter Coll, 85 St Nicholas Terrace, New York, NY 10027 USA

[5] CUNY Hunter Coll, Dept Chem & Biochem, 695 Pk Ave, New York, NY 10065 USA

[6] CUNY, Grad Ctr, PhD Program Chem, New York, NY 10016 USA

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 96期

基金：

欧盟第七框架计划;

关键词：

ASSEMBLED PEPTIDE NANOTUBES; DIPHENYLALANINE PEPTIDE; AMYLOID FIBRILS; PI-STACKING; NANOSTRUCTURES; AMPHIPHILES; TRIPEPTIDE; SYNERESIS; MOLECULES; INSIGHTS;

D O I：

10.1039/c6cc05821c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We demonstrate that the well-known self-assembling dipeptide diphenylalanine (FF) and its amidated derivative (FF-NH2) can form metastable hydrogels upon sonication of the dipeptide solutions. The hydrogels show instantaneous syneresis upon mechanical contact resulting in rapid expulsion of water and collapse into a semi-solid gel.

引用

页码：13889 / 13892

页数：4

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