Corneal electrolysis for recurrence of corneal stromal dystrophy after keratoplasty

被引:12
作者
Mashima, Y [1 ]
Kawai, M [1 ]
Yamada, M [1 ]
机构
[1] Keio Univ, Sch Med, Dept Ophthalmol, Shinjuku Ku, Tokyo 1608582, Japan
关键词
D O I
10.1136/bjo.86.3.273
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Aims: To evaluate corneal electrolysis as a treatment for recurrent diffuse corneal opacities at the host-graft interface of the stroma or at the subepithelial region in two types of granular corneal dystrophy (GCD). Methods: Recurrence developed at the host-graft interface of the stroma after lamellar keratoplasty in a patient with Avellino corneal dystrophy (ACD). At surgery,,the deep aspect of the graft in this patient was partially separated from host tissue to expose the deposits, with one third of the host-graft junction left intact. The graft was everted, and electrolysis was applied directly to remove the deposits attached to both surfaces of the host and the graft. Then the Waft was returned to its place and sutured. In two patients with homozygous ACD and one patient with the superficial variant of GCD, diffuse subepithelial opacities developed following penetrating keratoplasty. Electrolysis was applied directly to the corneal surface. Results: Deposits at the host-graft interface of the stroma and in the subepithelial region disappeared following treatment, and vision recovered in all patients. Conclusions: This method is a simple, easy, and inexpensive way to remove deposits that recur after lamellar or penetrating keratoplasty.
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收藏
页码:273 / 275
页数:3
相关论文
共 16 条
[1]   Recurrence of corneal dystrophy after excimer laser phototherapeutic keratectomy [J].
Dinh, R ;
Rapuano, CJ ;
Cohen, EJ ;
Laibson, PR .
OPHTHALMOLOGY, 1999, 106 (08) :1490-1497
[2]   Varied appearance of cornea of patients with corneal dystrophy associated with R124H mutation in the BIGH3 gene [J].
Konishi, M ;
Yamada, M ;
Nakamura, Y ;
Mashima, Y .
CORNEA, 1999, 18 (04) :424-429
[3]  
LYONS CJ, 1994, OPHTHALMOLOGY, V101, P1812
[4]   AIDS and the eye - A 10-year experience [J].
Maclean, H ;
Hall, AJH ;
McCombe, MF ;
Sandland, AM .
AUSTRALIAN AND NEW ZEALAND JOURNAL OF OPHTHALMOLOGY, 1996, 24 (01) :61-67
[5]  
Mannis MJ, 1997, CORNEA DIAGNOSIS MAN, V2, P1043
[6]   Severe form of juvenile corneal stromal dystrophy with homozygous R124H mutation in the keratoepithelin gene in five Japanese patients [J].
Mashima, Y ;
Konishi, M ;
Nakamura, Y ;
Imamura, Y ;
Yamada, M ;
Ogata, T ;
Kudoh, J ;
Shimizu, N .
BRITISH JOURNAL OF OPHTHALMOLOGY, 1998, 82 (11) :1280-1284
[7]  
Mashima Y, 1999, ARCH OPHTHALMOL-CHIC, V117, P90
[8]   Kerato-epithelin mutations in four 5q31-linked corneal dystrophies [J].
Munier, FL ;
Korvatska, E ;
Djemai, A ;
LePaslier, D ;
Zografos, L ;
Pescia, G ;
Schorderet, DF .
NATURE GENETICS, 1997, 15 (03) :247-251
[9]  
Nassaralla BA, 1996, J REFRACT SURG, V12, P795
[10]  
NII H, 1990, Folia Ophthalmologica Japonica, V41, P1134