Stem Cell-Based Tissue Replacement After Stroke Factual Necessity or Notorious Fiction?

被引:71
作者
Janowski, Miroslaw [1 ,2 ,3 ,4 ,5 ]
Wagner, Daniel-Christoph [6 ]
Boltze, Johannes [6 ,7 ]
机构
[1] Johns Hopkins Univ, Sch Med, Russell H Morgan Dept Radiol & Radiol Sci, Div MR Res, Baltimore, MD USA
[2] Johns Hopkins Univ, Sch Med, Cellular Imaging Sect, Baltimore, MD USA
[3] Johns Hopkins Univ, Sch Med, Vasc Biol Program, Inst Cell Engn, Baltimore, MD USA
[4] Polish Acad Sci, Mossakowski Med Res Ctr, NeuroRepair Dept, Warsaw, Poland
[5] Polish Acad Sci, Mossakowski Med Res Ctr, Dept Neurosurg, Warsaw, Poland
[6] Fraunhofer Inst Cell Therapy & Immunol, Translat Ctr Regenerat Med, Dept Cell Therapy, Leipzig, Germany
[7] Harvard Univ, Stroke & Neurovasc Regulat Lab, Massachussets Gen Hosp, Neurosci Ctr,Med Sch,Stroke & Neurovasc Regulat L, Charlestown, MA USA
关键词
brain; nerve regeneration; neurons; stem cell transplantation; stroke; tissue engineering; tissue-type plasminogen activator; ACUTE ISCHEMIC-STROKE; MESENCHYMAL STROMAL CELLS; FOCAL CEREBRAL-ISCHEMIA; NEUROVASCULAR NICHE; FUNCTIONAL RECOVERY; PARKINSONS-DISEASE; ENDOTHELIAL-CELLS; IMPROVE RECOVERY; IN-VITRO; AUTOIMMUNE ENCEPHALOMYELITIS;
D O I
10.1161/STROKEAHA.114.007803
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:2354 / 2363
页数:10
相关论文
共 101 条
[1]   STRIATAL GRAFTS IN INFARCT STRIATOPALLIDUM INCREASE GABA RELEASE, REORGANIZE GABA, RECEPTOR AND IMPROVE WATER-MAZE LEARNING IN THE RAT [J].
AIHARA, N ;
MIZUKAWA, K ;
KOIDE, K ;
MABE, H ;
NISHINO, H .
BRAIN RESEARCH BULLETIN, 1994, 33 (05) :483-488
[2]   The CCR2/CCL2 Interaction Mediates the Transendothelial Recruitment of Intravascularly Delivered Neural Stem Cells to the Ischemic Brain [J].
Andres, Robert H. ;
Choi, Raymond ;
Pendharkar, Arjun V. ;
Gaeta, Xavier ;
Wang, Nancy ;
Nathan, Jaya K. ;
Chua, Joshua Y. ;
Lee, Star W. ;
Palmer, Theo D. ;
Steinberg, Gary K. ;
Guzman, Raphael .
STROKE, 2011, 42 (10) :2923-U387
[3]   Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain [J].
Andres, Robert H. ;
Horie, Nobutaka ;
Slikker, William ;
Keren-Gill, Hadar ;
Zhan, Ke ;
Sun, Guohua ;
Manley, Nathan C. ;
Pereira, Marta P. ;
Sheikh, Lamiya A. ;
McMillan, Erin L. ;
Schaar, Bruce T. ;
Svendsen, Clive N. ;
Bliss, Tonya M. ;
Steinberg, Gary K. .
BRAIN, 2011, 134 :1777-1789
[4]   Neuroprotection in acute ischemic stroke - current status [J].
Auriel, E. ;
Bornstein, N. M. .
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2010, 14 (09) :2200-2202
[5]   Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms [J].
Bacigaluppi, Marco ;
Pluchino, Stefano ;
Jametti, Luca Peruzzotti ;
Kilic, Ertugrul ;
Kilic, Uelkan ;
Salani, Giuliana ;
Brambilla, Elena ;
West, Mark J. ;
Comi, Giancarlo ;
Martino, Gianvito ;
Hermann, Dirk M. .
BRAIN, 2009, 132 :2239-2251
[6]  
Balami JS, 2013, CNS NEUROL DISORD-DR, V12, P155
[7]   The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles [J].
Bible, Ellen ;
Chau, David Y. S. ;
Alexander, Morgan R. ;
Price, Jack ;
Shakesheff, Kevin M. ;
Modo, Michel .
BIOMATERIALS, 2009, 30 (16) :2985-2994
[8]   Transplantation of hNT neurons into the ischemic cortex: Cell survival and effect on sensorimotor behavior [J].
Bliss, TM ;
Kelly, S ;
Shah, AK ;
Foo, WC ;
Kohli, P ;
Stokes, C ;
Sun, GH ;
Ma, M ;
Masel, J ;
Kleppner, SR ;
Schallert, T ;
Palmer, T ;
Steinberg, GK .
JOURNAL OF NEUROSCIENCE RESEARCH, 2006, 83 (06) :1004-1014
[9]   Determination of the Therapeutic Time Window for Human Umbilical Cord Blood Mononuclear Cell Transplantation Following Experimental Stroke in Rats [J].
Boltze, Johannes ;
Schmidt, Uwe R. ;
Reich, Doreen M. ;
Kranz, Alexander ;
Reymann, Klaus G. ;
Strassburger, Maria ;
Lobsien, Donald ;
Wagner, Daniel-Christoph ;
Foerschler, Annette ;
Schaebitz, Wolf-Ruediger .
CELL TRANSPLANTATION, 2012, 21 (06) :1199-1211
[10]   Assessment of Neuroprotective Effects of Human Umbilical Cord Blood Mononuclear Cell Subpopulations In Vitro and In Vivo [J].
Boltze, Johannes ;
Reich, Doreen M. ;
Hau, Susann ;
Reymann, Klaus G. ;
Strassburger, Maria ;
Lobsien, Donald ;
Wagner, Daniel-Christoph ;
Kamprad, Manja ;
Stahl, Tobias .
CELL TRANSPLANTATION, 2012, 21 (04) :723-737