ALS : Management Problems

被引：18

作者：

Brent, Jonathan R. ^{[1
]}

Franz, Colin K. ^{[2
,3
]}

Coleman, John M., III ^{[4
]}

Ajroud-Driss, Senda ^{[1
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Dept Neurol, 303 East Chicago Ave, Chicago, IL 60611 USA

[2] Northwestern Univ, Dept Phys Med & Rehabilitat, Feinberg Sch Med, Chicago, IL 60611 USA

[3] Northwestern Univ, Shirley Ryan AbilityLab, Dept Neurol, Feinberg Sch Med, Chicago, IL 60611 USA

[4] Northwestern Univ, Div Pulm & Crit Care Med, Feinberg Sch Med, Chicago, IL 60611 USA

来源：

NEUROLOGIC CLINICS | 2020年 / 38卷 / 03期

关键词：

ALS; Dysphagia; Dysarthria; Spasticity; Noninvasive ventilation; Respiratory failure; Secretion management; Sialorrhea; AMYOTROPHIC-LATERAL-SCLEROSIS; QUALITY-OF-LIFE; CARE; GASTROSTOMY; SURVIVAL; THERAPY; IMPACT;

D O I：

10.1016/j.ncl.2020.03.013

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Amyotrophic lateral sclerosis (ALS) is a fatal disease with no cure; however, symptomatic management has an impact on quality of life and survival. Symptom management is best performed in a multidisciplinary care setting, where patients are evaluated by multiple health care professionals. Respiratory failure is a significant cause of morbidity and mortality in patients with ALS. Early initiation of noninvasive ventilation can prolong survival, and adequate use of airway clearance techniques can prevent respiratory infections. Preventing and treating weight loss caused by dysphagia may slow down disease progression, and expert management of spasticity from upper motor neuron dysfunction enhances patient well-being. © 2020 Elsevier Inc.

引用

页码：565 / 575

页数：11

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