MANDIBLE BROWN TUMOR CAUSED BY PRIMARY HYPERPARATHYROIDISM

Brown tumor is a uni or multi-focal bone lesion, which represents the terminal stage of the hyperparathyroidism-dependent bone pathology. It often appears as an expansive osteolytic lesion of the bone, commonly in the mandible, ribs, pelvis and femur. A 56 year-old male patient presented with an asymptomatic unilocular radiolucent lesion of the right mandible without teeth. The lesion had a diameter of about 3 cm, had sharply delimited margins and was surrounded by an osteosclerotic rim. Under local anesthesia, the lesion was extracted surgically. The microscopic diagnosis was brown tumor of the mandible. The following report describes a patient with secondary hyperparathyroidism who developed a brown tumor of the mandible, discuss the differential diagnosis, and review the literature.