Fertility after breast cancer

被引：36

作者：

Christinat, Alexandre ^{[1
]}

Pagani, Olivia ^{[1
]}

机构：

[1] Inst Oncol So Switzerland, Bellinzona, Switzerland

来源：

MATURITAS | 2012年 / 73卷 / 03期

关键词：

Breast cancer; Fertility conservation; GnRH; Amenorrhea; Breastfeeding; Pregnancy; CRYOPRESERVED OVARIAN TISSUE; YOUNG-WOMEN; PREMENOPAUSAL WOMEN; RANDOMIZED-TRIAL; ADJUVANT CHEMOTHERAPY; MENOPAUSAL SYMPTOMS; CONSERVING THERAPY; PROGNOSTIC IMPACT; HORMONE AGONIST; TERM PREGNANCY;

D O I：

10.1016/j.maturitas.2012.07.013

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Breast cancer is the most common tumor in childbearing women. In the last decades, considerable improvement in breast cancer-related death has been achieved with adjuvant therapies (chemotherapy, endocrine and targeted therapies, radiotherapy) but at cost of significant long-term sequels, including infertility. Reproductive issues are of great importance to young women, in particular for those who did not complete their families before breast cancer diagnosis: patients should be adequately informed at the time of diagnosis about the risk of infertility and the available methods for fertility preservation. This review will focus on incidence and impact of infertility secondary to breast cancer treatment, the available options for ovarian function preservation, including embryo and oocyte cryopreservation, ovarian tissue cryopreservation, and ovarian suppression with gonadotropin-releasing hormone agonists. We will also discuss the optimal time of subsequent pregnancy, the potential risks for the mother and the fetus, and the impact of therapies on breastfeeding. (c) 2012 Elsevier Ireland Ltd. All rights reserved.

引用

页码：191 / 196

页数：6

共 83 条

[1] The Effects of Paclitaxel, Dose Density, and Trastuzumab on Treatment-Related Amenorrhea in Premenopausal Women With Breast Cancer [J].

Abusief, Mary E. ;

Missmer, Stacey A. ;

Ginsburg, Elizabeth S. ;

Weeks, Jane C. ;

Partridge, Ann H. .

CANCER, 2010, 116 (04) :791-798

[2] Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials [J].

Albain, K. ;

Anderson, S. ;

Arriagada, R. ;

Barlow, W. ;

Bergh, J. ;

Bliss, J. ;

Buyse, M. ;

Cameron, D. ;

Carrasco, E. ;

Clarke, M. ;

Correa, C. ;

Coates, A. ;

Collins, R. ;

Costantino, J. ;

Cutter, D. ;

Cuzick, J. ;

Darby, S. ;

Davidson, N. ;

Davies, C. ;

Davies, K. ;

Delmestri, A. ;

Di Leo, A. ;

Dowsett, M. ;

Elphinstone, P. ;

Evans, V. ;

Ewertz, M. ;

Gelber, R. ;

Gettins, L. ;

Geyer, C. ;

Goldhirsch, A. ;

Godwin, J. ;

Gray, R. ;

Gregory, C. ;

Hayes, D. ;

Hill, C. ;

Ingle, J. ;

Jakesz, R. ;

James, S. ;

Kaufmann, M. ;

Kerr, A. ;

MacKinnon, E. ;

McGale, P. ;

McHugh, T. ;

Norton, L. ;

Ohashi, Y. ;

Paik, S. ;

Pan, H. C. ;

Perez, E. ;

Peto, R. ;

Piccart, M. .

LANCET, 2012, 379 (9814) :432-444

[3]

American Society of Pediatrics, 2012, PEDIATRICS, V129, pe827

[4] Fertility preservation in girls and young women [J].

Anderson, Richard A. ;

Wallace, W. Hamish B. .

CLINICAL ENDOCRINOLOGY, 2011, 75 (04) :409-419

[5] Pretreatment Serum Anti-Mullerian Hormone Predicts Long-Term Ovarian Function and Bone Mass after Chemotherapy for Early Breast Cancer [J].

Anderson, Richard A. ;

Cameron, David A. .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2011, 96 (05) :1336-1343

[6] Pregnancies, breast-feeding, and breast cancer risk in the international BRCA1/2 carrier cohort study (IBCCS) [J].

Andrieu, Nadine ;

Goldgar, David E. ;

Easton, Douglas F. ;

Rookus, Matti ;

Brohet, Richard ;

Antoniou, Antonis C. ;

Peock, Susan ;

Evans, Gareth ;

Eccles, Diana ;

Douglas, Fiona ;

Nogues, Catherine ;

Gauthier-Villars, Marion ;

Chompret, Agnes ;

van Leeuwen, Flora E. ;

Kluijt, Irina ;

Benitez, Javier ;

Arver, Brita ;

Olah, Edith ;

Chang-Claude, Jenny .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2006, 98 (08) :535-544

[7]

[Anonymous], 2008, FERTILITY STERILITY, V90, pS60

[8] Gene Expression Patterns in the Human Breast after Pregnancy [J].

Asztalos, Szilard ;

Gann, Peter H. ;

Hayes, Meghan K. ;

Nonn, Larisa ;

Beam, Craig A. ;

Dai, Yang ;

Wiley, Elizabeth L. ;

Tonetti, Debra A. .

CANCER PREVENTION RESEARCH, 2010, 3 (03) :301-311

[9] Psychosocial problems among younger women with breast cancer [J].

Avis, NE ;

Crawford, S ;

Manuel, J .

PSYCHO-ONCOLOGY, 2004, 13 (05) :295-308

[10] Long-term toxic effects of adjuvant chemotherapy in breast cancer [J].

Azim, H. A., Jr. ;

de Azambuja, E. ;

Colozza, M. ;

Bines, J. ;

Piccart, M. J. .

ANNALS OF ONCOLOGY, 2011, 22 (09) :1939-1947

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