Facile quantification of enantiomeric excess and concentration with indicator-displacement assays:: An example in the analyses of α-hydroxyacids

被引：198
作者：
Zhu, L [1 ]
Anslyn, EV [1 ]
机构：
[1] Univ Texas, Dept Chem & Biochem, Austin, TX 78712 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 12期
关键词：
D O I：
10.1021/ja031839s
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An enantioselective indicator-displacement assay was developed to determine enantiomeric excess (ee) and concentration of α-hydroxyacid samples with two independent absorption measurements. The inherent relationship between the absorbance of the indicator-displacement ensemble and the overall concentration and ee of the analyte was established through solution equilibria. Copyright © 2004 American Chemical Society.
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收藏
页码：3676 / 3677
页数：2
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