Peptide library based on calix[4]arene

被引：36

作者：

Hioki, H ^{[1
]}

Yamada, T ^{[1
]}

Fujioka, C ^{[1
]}

Kodama, M ^{[1
]}

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Yamashiro, Tokushima 7708514, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 37期

关键词：

calixarenes; peptides; combinatorial chemistry; molecular recognition;

D O I：

10.1016/S0040-4039(99)01368-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A calix[4]arene library consisting of ca. 50000 members was synthesized using 15 amino acids. Screening of the library for binding dye-labeled oligopeptides indicated that some peptidocalix[4]arenes selectively bind specific oligopeptides. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：6821 / 6825

页数：5

共 18 条

[1] PEPTIDOSTEROIDAL RECEPTORS FOR OPIOID-PEPTIDES - SEQUENCE-SELECTIVE BINDING USING A SYNTHETIC RECEPTOR LIBRARY [J].

BOYCE, R ;

LI, G ;

NESTLER, HP ;

SUENAGA, T ;

STILL, WC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (17) :7955-7956

[2] Sequence-selective peptide binding with a peptido-A,B-trans-steroidal receptor selected from an encoded combinatorial receptor library [J].

Cheng, YA ;

Suenaga, T ;

Still, WC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (07) :1813-1814

[3] Screening an inverted peptide library in water with a guanidinium-based tweezer receptor [J].

Davies, M ;

Bonnat, M ;

Guillier, F ;

Kilburn, JD ;

Bradley, M .

JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (24) :8696-8703

[4]

Gennari C, 1997, LIEBIGS ANN-RECL, P637

[5] A COMBINATORIAL LIBRARY APPROACH TO ARTIFICIAL RECEPTOR DESIGN [J].

GOODMAN, MS ;

JUBIAN, V ;

LINTON, B ;

HAMILTON, AD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (46) :11610-11611

[6] CALIXARENES-9 - CONFORMATIONAL ISOMERS OF THE ETHERS AND ESTERS OF CALIX[4]ARENES [J].

GUTSCHE, CD ;

DHAWAN, B ;

LEVINE, JA ;

NO, KH ;

BAUER, LJ .

TETRAHEDRON, 1983, 39 (03) :409-426

[7]

Haino T, 1998, SYNLETT, P1016

[8] Novel cavity design using calix[n]arene skeletons: Toward molecular recognition and metal binding [J].

Ikeda, A ;

Shinkai, S .

CHEMICAL REVIEWS, 1997, 97 (05) :1713-1734

[9] Cyclopeptide libraries as new chiral selectors in capillary electrophoresis [J].

Jung, G ;

Hofstetter, H ;

Feiertag, S ;

Stoll, D ;

Hofstetter, O ;

Wiesmuller, KH ;

Schurig, V .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1996, 35 (18) :2148-2150

[10]

Kubo Y, 1999, SYNLETT, P161

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