Palladium-Catalyzed Oxidative Cycloaddition through C-H/N-H Activation: Access to Benzazepines

被引：116

作者：

Wang, Lei ^{[1
]}

Huang, Jiayao ^{[1
]}

Peng, Shiyong ^{[1
]}

Liu, Hui ^{[2
]}

Jiang, Xuefeng ^{[2
]}

Wang, Jian ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

[2] E China Normal Univ, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 06期

基金：

新加坡国家研究基金会;

关键词：

benzazepine; C-H activation; N-H activation; oxidative cycloaddition; palladium; N BOND FORMATION; ISOQUINOLONE SYNTHESIS; INTERNAL ALKYNES; ATOM ECONOMY; O BOND; FUNCTIONALIZATION; INDOLES; CHEMISTRY; ARYLATION; CLEAVAGE;

D O I：

10.1002/anie.201208076

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Rings beget rings: Benzazepines, well-known structural design elements in medicinal chemistry, are readily prepared by a one-pot palladium-catalyzed oxidative cycloaddition of isatins with various alkynes. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1768 / 1772

页数：5

共 50 条

[31] Indoles from Simple Anilines and Alkynes: Palladium-Catalyzed C-H Activation Using Dioxygen as the Oxidant [J].

Shi, Zhuangzhi ;

Zhang, Chun ;

Li, Si ;

Pan, Delin ;

Ding, Shengtao ;

Cui, Yuxin ;

Jiao, Ning .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (25) :4572-4576

[32] Access to Chiral Hydropyrimidines through Palladium-Catalyzed Asymmetric Allylic C-H Amination [J].

Wang, Pu-Sheng ;

Shen, Meng-Lan ;

Wang, Tian-Ci ;

Lin, Hua-Chen ;

Gong, Liu-Zhu .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 56 (50) :16032-16036

[33] Palladium-catalyzed oxidative arylation of chromones via a double C-H activation: an expedient approach to flavones [J].

Kim, Ko Hoon ;

Lee, Hyun Seung ;

Kim, Se Hee ;

Kim, Jae Nyoung .

TETRAHEDRON LETTERS, 2012, 53 (22) :2761-2764

[34] Palladium-catalyzed oxidative cyclopropanation of enamides and norbornenes initiated by C-H activation [J].

Chen, Ming ;

Zhao, Mi-Na ;

Zhang, Yao-Du ;

Ren, Zhi-Hui ;

Guan, Zheng-Hui .

SCIENCE CHINA-CHEMISTRY, 2018, 61 (06) :695-701

[35] Fused Pyrrolo[2,3-d]pyrimidines (7-Deazapurines) by Palladium-Catalyzed Direct N-H and C-H Arylation Reactions [J].

Dodonova, Jelena ;

Tumkevicius, Sigitas .

SYNTHESIS-STUTTGART, 2017, 49 (11) :2523-2534

[36] One-Pot Formation of C-C and C-N Bonds through Palladium-Catalyzed Dual C-H Activation: Synthesis of Phenanthridinones [J].

Wang, Guan-Wu ;

Yuan, Ting-Ting ;

Li, Dan-Dan .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (06) :1380-1383

[37] Palladium-Catalyzed Double C-H Activation Directed by Sulfoxides in the Synthesis of Dibenzothiophenes [J].

Samanta, Rajarshi ;

Antonchick, Andrey P. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (22) :5217-5220

[38] Synthesis of indoles, indolines, and carbazoles via palladium-catalyzed C-H activation [J].

Rago, Alexander J. ;

Dong, Guangbin .

GREEN SYNTHESIS AND CATALYSIS, 2021, 2 (02) :216-227

[39] Modern Palladium-Catalyzed Transformations Involving C-H Activation and Subsequent Annulation [J].

Thombal, Raju S. ;

Rubio, Peter Yuosef M. ;

Lee, Daesung ;

Maiti, Debabrata ;

Lee, Yong Rok .

ACS CATALYSIS, 2022, 12 (09) :5217-5230

[40] SYNTHESIS OF PHENANTHRIDINES AND RELATED COMPOUNDS BY PALLADIUM-CATALYZED DIRECT COUPLING VIA C-H AND N-H BOND CLEAVAGES [J].

Takeda, Daisuke ;

Hirano, Koji ;

Satoh, Tetsuya ;

Miura, Masahiro .

HETEROCYCLES, 2012, 86 (01) :487-496

← 1 2 3 4 5 →