Diversity of Bipolaris Species in Clinical Samples in the United States and Their Antifungal Susceptibility Profiles

被引：54

作者：

da Cunha, K. C. ^{[1
]}

Sutton, D. A. ^{[2
]}

Fothergill, A. W. ^{[2
]}

Cano, J. ^{[1
]}

Gene, J. ^{[1
]}

Madrid, H. ^{[3
]}

De Hoog, S. ^{[3
]}

Crous, P. W. ^{[3
]}

Guarro, J. ^{[1
]}

机构：

[1] Univ Rovira & Virgili, Sch Med, Mycol Unit, E-43201 Reus, Spain

[2] Univ Texas Hlth Sci Ctr San Antonio, Fungus Testing Lab, San Antonio, TX 78229 USA

[3] CBS KNAW Fungal Biodivers Ctr, Utrecht, Netherlands

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 12期

关键词：

FUNGAL SINUSITIS; DISSEMINATED INFECTION; AMPHOTERICIN-B; SPICIFERA; PHEOHYPHOMYCOSIS; AUSTRALIENSIS; ITRACONAZOLE; VORICONAZOLE;

D O I：

10.1128/JCM.01965-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A set of 104 isolates from human clinical samples from the United States, morphologically compatible with Bipolaris, were morphologically and molecularly identified through the sequence analysis of the internal transcribed space (ITS) region of the nuclear ribosomal DNA (rDNA). The predominant species was Bipolaris spicifera (67.3%), followed by B. hawaiiensis (18.2%), B. cynodontis (8.6%), B. micropus (2.9%), B. australiensis (2%), and B. setariae (1%). Bipolaris cynodontis, B. micropus, and B. setariae represent new records from clinical samples. The most common anatomical sites where isolates were recovered were the nasal region (30.7%), skin (19.2%), lungs (14.4%), and eyes (12.5%). The antifungal susceptibilities of 5 species of Bipolaris to 9 drugs are provided. With the exception of fluconazole and flucytosine, the antifungals tested showed good activity.

引用

页码：4061 / 4066

页数：6

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