THE GLUR2 SUBUNIT OF AMPA RECEPTORS: SYNAPTIC ROLE

被引:45
作者
Bassani, S. [1 ]
Valnegri, P. [1 ]
Beretta, F. [1 ]
Passafaro, M. [1 ]
机构
[1] Univ Milan, Dept Pharmacol, CNR, Inst Neurosci, Milan, Italy
关键词
LONG-TERM DEPRESSION; ETHYLMALEIMIDE-SENSITIVE FACTOR; GLUTAMATE-OPERATED CHANNELS; HIPPOCAMPAL-NEURONS; INTERACTING PROTEIN; REGULATORY PROTEINS; DENDRITIC SPINES; BINDING PROTEIN; C-TERMINUS; IN-VIVO;
D O I
10.1016/j.neuroscience.2008.10.007
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Ampa receptors mediate the majority of excitatory synaptic transmission in the brain. Thus, the mechanisms that control the developmental and activity-dependent changes in the functional synaptic expression of AMPA receptors are of fundamental importance. Here we focus on the role of GluR2 subunit in synaptic function and plasticity. (C) 2009 IBRO. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:55 / 61
页数:7
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