Estimating Effective Dose of Radiation From Pediatric Cardiac CT Angiography Using a 64-MDCT Scanner: New Conversion Factors Relating Dose-Length Product to Effective Dose

被引:17
|
作者
Trattner, Sigal [1 ]
Chelliah, Anjali [2 ]
Prinsen, Peter [3 ]
Ruzal-Shapiro, Carrie B. [4 ]
Xu, Yanping [5 ]
Jambawalikar, Sachin [4 ]
Amurao, Maxwell [6 ]
Einstein, Andrew J. [1 ,4 ,7 ]
机构
[1] Columbia Univ, Dept Med, Div Cardiol, Med Ctr, 622 W 168th St,PH 10-203A, New York, NY 10032 USA
[2] Columbia Univ, Med Ctr, New York Presbyterian Morgan Stanley Childrens Ho, Dept Pediat,Pediat Cardiol Div, New York, NY USA
[3] Philips Healthcare Res, Eindhoven, Netherlands
[4] Columbia Univ, Dept Radiol, Med Ctr, 622 W 168th St,PH 10-203A, New York, NY 10032 USA
[5] Columbia Univ, Ctr Radiol Res, Radiol Res Accelerator Facil, Irvington, NY USA
[6] Columbia Univ, Med Ctr, Radiat Safety Off, New York, NY USA
[7] New York Presbyterian Hosp, 622 W 168th St,PH 10-203A, New York, NY 10032 USA
基金
美国国家卫生研究院;
关键词
conversion factor; dose-length product; effective dose; pediatric cardiac CT; radiation; COMPUTED-TOMOGRAPHY ANGIOGRAPHY; SUBSEQUENT RISK; CANCER-RISK; CHILDREN; ACCURACY; INFANTS; CHILDHOOD; EXPOSURE; DISEASE; TRENDS;
D O I
10.2214/AJR.15.15908
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
OBJECTIVE. The purpose of this study is to determine the conversion factors that enable accurate estimation of the effective dose (ED) used for cardiac 64-MDCT angiography performed for children. MATERIALS AND METHODS. Anthropomorphic phantoms representative of 1- and 10-year-old children, with 50 metal oxide semiconductor field-effect transistor dosimeters placed in organs, underwent scanning performed using a 64-MDCT scanner with different routine clinical cardiac scan modes and x-ray tube potentials. Organ doses were used to calculate the ED on the basis of weighting factors published in 1991 in International Commission on Radiological Protection (ICRP) publication 60 and in 2007 in ICRP publication 103. The EDs and the scanner-reported dose-length products were used to determine conversion factors for each scan mode. The effect of infant heart rate on the ED and the conversion factors was also assessed. RESULTS. The mean conversion factors calculated using the current definition of ED that appeared in ICRP publication 103 were as follows: 0.099 mSv center dot mGy(-1) center dot cm(-1), for the 1-year-old phantom, and 0.049 mSv center dot mGy(-1) center dot cm(-1), for the 10-year-old phantom. These conversion factors were a mean of 37% higher than the corresponding conversion factors calculated using the older definition of ED that appeared in ICRP publication 60. Varying the heart rate did not influence the ED or the conversion factors. CONCLUSION. Conversion factors determined using the definition of ED in ICRP publication 103 and cardiac, rather than chest, scan coverage suggest that the radiation doses that children receive from cardiac CT performed using a contemporary 64-MDCT scanner are higher than the radiation doses previously reported when older chest conversion factors were used. Additional up-to-date pediatric cardiac CT conversion factors are required for use with other contemporary CT scanners and patients of different age ranges.
引用
收藏
页码:585 / 594
页数:10
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