HIV-1 subtypes in Yugoslavia

被引：21

作者：

Stanojevic, M

Papa, A

Papadimitriou, E

Zerjav, S

Jevtovic, D

Salemovic, D

Jovanovic, T

Antoniadis, A

机构：

[1] Univ Belgrade, Sch Med, Inst Microbiol & Immunol, YU-11000 Belgrade, Yugoslavia

[2] Aristotle Univ Thessaloniki, Sch Med, Natl AIDS Reference Lab No Greece, Dept Microbiol, Thessaloniki 54006, Greece

[3] Inst Infect & Trop Dis CCS, YU-11000 Belgrade, Yugoslavia

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 2002年 / 18卷 / 07期

关键词：

D O I：

10.1089/088922202317406673

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To gain insight concerning the genetic diversity of HIV-1 viruses associated with the HIV-1 epidemic in Yugoslavia, 45 specimens from HIV-1-infected individuals were classified into subtypes by sequence-based phylogenetic analysis of the polymerase (pol) region of the viral genome. Forty-one of 45 specimens (91.2%) were identified as pol subtype B, 2 of 45 as subtype C (4.4%), 1 of 45 as CRF01_AE (2.2%), and 1 as CRF02-AG recombinant (2.2%). Nucleotide divergence among subtype B sequences was 4.8%. Results of this study show that among HIV-1-infected patients in Yugoslavia subtype B predominates (91.5%), whereas non-B subtypes are present at a low percentage, mostly related to travel abroad.

引用

页码：519 / 522

页数：4

共 12 条

[1]

[Anonymous], HIV Sequence Database

[2] An HIV type 1 subtype a strain of low genetic diversity continues to spread among injecting drug users in Russia: study of the new local outbreaks in Moscow and Irkutsk [J].

Bobkov, A ;

Kazennova, E ;

Khanina, T ;

Bobkova, M ;

Selimova, L ;

Kravchenko, A ;

Pokrovsky, V ;

Weber, J .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2001, 17 (03) :257-261

[3] An HIV type 1 epidemic among injecting drug users in the former Soviet Union caused by a homogeneous subtype A strain [J].

Bobkov, A ;

CheingsongPopov, R ;

Selimova, L ;

Ladnaya, N ;

Kazennova, E ;

Kravchenko, A ;

Fedotov, E ;

Saukhat, S ;

Zverev, S ;

Pokrovsky, V ;

Weber, J .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1997, 13 (14) :1195-1201

[4]

COBIC P, 1990, J ACQ IMMUN DEF SYND, V3, P1197

[5]

FELSENSTEIN J, 1993, PHYLIP VERS 3 5C

[6] GENETIC-ANALYSIS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 STRAINS FROM PATIENTS IN CYPRUS - IDENTIFICATION OF A NEW SUBTYPE DESIGNATED SUBTYPE-I [J].

KOSTRIKIS, LG ;

BAGDADES, E ;

CAO, YZ ;

ZHANG, LQ ;

DIMITRIOU, D ;

HO, DD .

JOURNAL OF VIROLOGY, 1995, 69 (10) :6122-6130

[7]

Op De Coul E, 2000, AIDS RES HUM RETROV, V16, P327

[8]

PAPA A, 2002, IN PRESS VIRUS RES

[9]

*WHO UNAIDS, WHO UNAIDS EP FACT S

[10] Identification of non-B human immunodeficiency virus type 1 subtypes in rural Georgia [J].

Womack, C ;

Roth, W ;

Newman, C ;

Rissing, JP ;

Lovell, R ;

Haburchak, D ;

Essex, M ;

Bond, VC .

JOURNAL OF INFECTIOUS DISEASES, 2001, 183 (01) :138-142

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