Microwave-Promoted Synthesis of Some Novel 4-(4-Methyl-phenyl)-Substituted Phthalazin-1-one Derivatives

被引：4

作者：

Havaldar, Freddy H. ^{[1
]}

Dabholkar, Bhushan V. ^{[1
]}

Mule, Ganesh B. ^{[1
]}

机构：

[1] St Xaviers Coll, Dept Chem, Nadkarni Sacasa Res Lab, Bombay, Maharashtra, India

来源：

SYNTHETIC COMMUNICATIONS | 2013年 / 43卷 / 08期

关键词：

Alkylation; bicyclic compounds; cyclization; heterocycles; phase-transfer catalyst; IRRADIATION; AGENTS;

D O I：

10.1080/00397911.2011.622847

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this study, a series of 4-(4-methyl-phenyl)-substituted phthalazin-1-one derivatives have been synthesized with the combination of rapid microwave synthesis and phase-transfer catalyst methodology, which is characterized by very short reaction times and easy workup procedures and which can be exploited to generate some novel phthalazinone heterocycles. Substituted phthalazin-1-one derivatives have been synthesized from phthalyl derivatives as starting material. The structures of these compounds were confirmed by NMR and mass spectral studies.

引用

页码：1127 / 1137

页数：11

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