Akt and intermediate filaments inhibit autophagy and promote tumorigenesis through Beclin 1/14-3-3 sequestration

被引：0
|
作者：
Wang, R. C. [1 ]
Wei, Y. [2 ]
An, Z. [2 ]
Zou, Z. [2 ]
White, M. [1 ]
Reichelt, J. [3 ]
Levine, B. [2 ]
机构：
[1] UT Southwestern, Dallas, TX USA
[2] UT Southwestern, Ctr Autophagy Res, Dallas, TX USA
[3] Newcastle Univ, Inst Cellular Med, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2013年 / 133卷
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
370
引用
收藏
页码：S63 / S63
页数：1
相关论文
共 50 条
  • [31] Metabolic-Stress-Induced Rearrangement of the 14-3-3ζ Interactome Promotes Autophagy via a ULK1-and AMPK-Regulated 14-3-3ζ Interaction with Phosphorylated Atg9
    Weerasekara, Vajira K.
    Panek, David J.
    Broadbent, David G.
    Mortenson, Jeffrey B.
    Mathis, Andrew D.
    Logan, Gideon N.
    Prince, John T.
    Thomson, David M.
    Thompson, J. Will
    Andersen, Joshua L.
    MOLECULAR AND CELLULAR BIOLOGY, 2014, 34 (24) : 4379 - 4388
  • [32] Light-dependent phosphorylation of THRUMIN1 regulates its association with actin filaments and 14-3-3 proteins
    Dwyer, Matthew E.
    Hangarter, Roger P.
    PLANT PHYSIOLOGY, 2021, 187 (03) : 1445 - 1461
  • [33] AKT Blocks SIK1-Mediated Repression of STAT3 to Promote Breast Tumorigenesis
    Sun, Zicheng
    Jiang, Qiwei
    Gao, Bing
    Zhang, Xiaomei
    Bu, Lang
    Wang, Lei
    Lin, Ying
    Xie, Wei
    Li, Jie
    Guo, Jianping
    CANCER RESEARCH, 2023, 83 (08) : 1264 - 1279
  • [34] Selective 14-3-3γ Upregulation Promotes Beclin-1-LC3-Autophagic Influx via β-Catenin Interaction in Starved Neurons In Vitro and In Vivo
    Xin Xin Xiong
    Dian Xing Hu
    Lu Xu
    Huang Lin
    Yu Zhang
    Chun Yang Li
    Xiao Qian Chen
    Neurochemical Research, 2019, 44 : 849 - 858
  • [35] Inhibition of 14-3-3ε by K50 acetylation activates YAP1 to promote cholangiocarcinoma growth
    Fan, Kun
    Zhu, Kaihua
    Wang, Jiwen
    Ni, Xiaojian
    Shen, Sheng
    Gong, Zijun
    Cheng, Xi
    Zhang, Cheng
    Liu, Han
    Suo, Tao
    Ni, Xiaoling
    Liu, Houbao
    EXPERIMENTAL CELL RESEARCH, 2022, 421 (02)
  • [36] Selective 14-3-3 Upregulation Promotes Beclin-1-LC3-Autophagic Influx via -Catenin Interaction in Starved Neurons In Vitro and In Vivo
    Xiong, Xin Xin
    Hu, Dian Xing
    Xu, Lu
    Lin, Huang
    Zhang, Yu
    Li, Chun Yang
    Chen, Xiao Qian
    NEUROCHEMICAL RESEARCH, 2019, 44 (04) : 849 - 858
  • [37] 14-3-3σ regulates B-cell homeostasis through stabilization of FOXO1
    Su, Yu-Wen
    Hao, Zhenyue
    Hirao, Atsushi
    Yamamoto, Kazuo
    Lin, Wen-Jye
    Young, Ashley
    Duncan, Gordon S.
    Yoshida, Hiroki
    Wakeham, Andrew
    Lang, Philipp A.
    Murakami, Kiichi
    Ohashi, Pamela
    Mak, Tak W.
    Hermeking, Heiko
    Vogelstein, Bert
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (04) : 1555 - 1560
  • [38] ANCA, through the activation of PI3Kγ and MTOR, promote neutrophil exocytosis and inhibit autophagy in vitro
    Holden, N. J.
    Bhattacharjee, D.
    Morgan, M. D.
    Harper, L.
    Savage, C. O. S.
    Williams, J. M.
    IMMUNOLOGY, 2011, 135 : 92 - 92
  • [39] Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway
    Zhangxiao Peng
    Yan Wang
    Jianhui Fan
    Xuejing Lin
    Chunying Liu
    Yang Xu
    Weidan Ji
    Chao Yan
    Changqing Su
    Scientific Reports, 7
  • [40] Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway
    Peng, Zhangxiao
    Wang, Yan
    Fan, Jianhui
    Lin, Xuejing
    Liu, Chunying
    Xu, Yang
    Ji, Weidan
    Yan, Chao
    Su, Changqing
    SCIENTIFIC REPORTS, 2017, 7
12345