A green synthesis of 3,4-dihydropyrimidine-2(1H)-one/thione derivatives using nanosilica-supported tin(II) chloride as a heterogeneous nanocatalyst

被引：46

作者：

Ghomi, Javad Safaei ^{[1
]}

Teymuri, Raheleh ^{[1
]}

Ziarati, Abolfazl ^{[1
]}

机构：

[1] Univ Kashan, Fac Chem, Dept Organ Chem, Kashan 51167, Iran

来源：

MONATSHEFTE FUR CHEMIE | 2013年 / 144卷 / 12期

关键词：

Nano silica-supported tin(II) chloride; Heterogeneous catalysis; Biginelli reaction; One-pot synthesis; ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; MAGNETICALLY RECOVERABLE CATALYST; BIGINELLI REACTION; REUSABLE CATALYST; IMPROVED PROTOCOL; SULFURIC-ACID; EFFICIENT; DIHYDROPYRIMIDINONES; 3,4-DIHYDROPYRIMIDIN-2(1H)-ONES;

D O I：

10.1007/s00706-013-1068-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Efficient, green, and straightforward synthesis of 3,4-dihydropyrimidine-2(1H)-one/thione derivatives under favorable conditions has been achieved by reaction of urea/thiourea, aldehydes, and ethyl acetoacetate, using the synthetic potential of nanosilica-supported tin(II) chloride. It is noteworthy that the procedure has many advantages, for example excellent product yields, short reaction time, easy isolation of products, and reusability of catalyst. .

引用

页码：1865 / 1870

页数：6

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