A green synthesis of 3,4-dihydropyrimidine-2(1H)-one/thione derivatives using nanosilica-supported tin(II) chloride as a heterogeneous nanocatalyst

被引：44
|
作者：
Ghomi, Javad Safaei [1 ]
Teymuri, Raheleh [1 ]
Ziarati, Abolfazl [1 ]
机构：
[1] Univ Kashan, Fac Chem, Dept Organ Chem, Kashan 51167, Iran
来源：
MONATSHEFTE FUR CHEMIE | 2013年 / 144卷 / 12期
关键词：
Nano silica-supported tin(II) chloride; Heterogeneous catalysis; Biginelli reaction; One-pot synthesis; ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; MAGNETICALLY RECOVERABLE CATALYST; BIGINELLI REACTION; REUSABLE CATALYST; IMPROVED PROTOCOL; SULFURIC-ACID; EFFICIENT; DIHYDROPYRIMIDINONES; 3,4-DIHYDROPYRIMIDIN-2(1H)-ONES;
D O I：
10.1007/s00706-013-1068-6
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Efficient, green, and straightforward synthesis of 3,4-dihydropyrimidine-2(1H)-one/thione derivatives under favorable conditions has been achieved by reaction of urea/thiourea, aldehydes, and ethyl acetoacetate, using the synthetic potential of nanosilica-supported tin(II) chloride. It is noteworthy that the procedure has many advantages, for example excellent product yields, short reaction time, easy isolation of products, and reusability of catalyst. .
引用
收藏
页码：1865 / 1870
页数：6
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