Screening for chronic kidney disease can be of help to prevent atherosclerotic end organ damage

被引:14
作者
Ozyilmaz, Akin
de Jong, Paul E. [1 ]
Gansevoort, Ronald T.
机构
[1] Univ Groningen, Univ Med Ctr Groningen, Dept Med, Div Nephrol, NL-9713 AV Groningen, Netherlands
关键词
albuminuria; chronic kidney disease; cardiovascular disease; eGFR; screening; URINARY ALBUMIN EXCRETION; TYPE-2; DIABETIC-NEPHROPATHY; GLOMERULAR-FILTRATION-RATE; BLOOD-PRESSURE; RENAL-DISEASE; CARDIOVASCULAR MORTALITY; RISK; PROGRESSION; MICROALBUMINURIA; HYPERTENSION;
D O I
10.1093/ndt/gfs438
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Atherosclerotic damage to the kidney is one of the most prevalent causes of chronic kidney disease and ultimately kidney failure. It frequently coincides with atherosclerotic damage to the heart, the brain and the lower extremities. In fact, the severity of the damage in the various end organs runs in parallel. As damage to the kidney is easy to measure by monitoring albuminuria and eGFR, and as the early phases of kidney damage frequently precede the alarming symptomatology in the heart, brain and peripheral vasculature, we argue that the nephrologist should consider taking the lead in better organizing early detection and management of CKD. The nephrologist can guide the general practitioner and general health care workers to offer better preventive care to the subjects at risk of progressive atherosclerotic end-organ damage.
引用
收藏
页码:4046 / 4052
页数:7
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