Skin telocytes

被引:106
|
作者
Rusu, M. C. [1 ]
Mirancea, N. [2 ]
Manoiu, V. S. [3 ]
Valcu, M. [4 ]
Nicolescu, M. I. [5 ,6 ]
Paduraru, D. [7 ]
机构
[1] Univ Med & Pharm Carol Davila, Discipline Anat, Dept MD 01, RO-050474 Bucharest, Romania
[2] Acad Romana, Inst Biol, Plant & Anim Cytobiol Dept, Bucharest, Romania
[3] Natl Inst Res & Dev Biol Sci, Dept Cellular & Mol Biol, Bucharest, Romania
[4] Univ Med & Pharm Carol Davila, Clin Plast Surg & Reconstruct Microsurg, Bucharest Emergency Hosp, Fac Med, RO-050474 Bucharest, Romania
[5] Victor Babes Natl Inst Pathol, Dept Mol Med, Bucharest, Romania
[6] Univ Med & Pharm Carol Davila, Cellular & Mol Med Dept, RO-050474 Bucharest, Romania
[7] Gr T Popa Univ Med & Pharm, Dept Anat, Iasi, Romania
关键词
Dermis; Mast cell; TEM; Fibroblast; Adipocyte; Elastic fibers; CAJAL-LIKE-CELLS; INTERSTITIAL-CELLS; FALLOPIAN-TUBE; ICLC; MYOCARDIUM;
D O I
10.1016/j.aanat.2011.11.007
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
A distinctive stromal cell-type, the telocyte (TC), has recently been described to send specific long prolongations (telopodes) alternating thin segments (podomers) with dilations (podoms). Even though one would expect TCs to be identified in various stromal tissues, there were not yet reported evidence of skin TCs. We aimed to check for the presence of TCs in human skin dermis. Transmission electron microscopy revealed the presence in dermis of TCs projecting specific telopodes. Skin TCs were closely related to or contacting fibroblasts, mast cells, adipocytes, and connective fiber bundles (collagenous and elastic). As it appears, skin TCs exist and are related to other stromal cells. The structural association of TCs to elastic fibers deserves further investigation. (c) 2011 Elsevier GmbH. All rights reserved.
引用
收藏
页码:359 / 367
页数:9
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