One-pot Three Component Synthesis of Polyfluoroarylated Arylacetates via VNSAr-SNAr Reaction

被引：6
|
作者：
Xiong Yang [1 ]
Wu Jingjing [2 ]
Xiao Senhan [1 ]
Cao Song [1 ]
机构：
[1] E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China
[2] Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai 201418, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2012年 / 30卷 / 12期
基金：
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词：
2-polyfluoroaryl arylacetates; three-component reaction; VNSAr-SNAr reaction; functionalization of the C?F bond; VICARIOUS NUCLEOPHILIC-SUBSTITUTION; PALLADIUM-CATALYZED ARYLATION; ACID-ESTERS; BENZYLPHOSPHINE OXIDES; ALPHA-ARYLATION; HYDROGEN; DERIVATIVES; 1,2,3-TRIAZOLES; FLUORINE; ANALOGS;
D O I：
10.1002/cjoc.201201044
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A series of 2-polyfluoroaryl arylacetates were synthesized by a one-pot three-component VNSAr-SNAr reaction of polyfluoroarenes, ethyl 2-chloropropionate, and ortho-substituted nitrobenzenes.
引用
收藏
页码：2747 / 2751
页数：5
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