Rh-Catalyzed Denitrogenative Reaction of N-Sulfonyl-1,2,3-triazoles with Isatoic Anhydrides and Oxadiazolones

被引：37

作者：

Pal, Kuntal ^{[1
]}

Hoque, Abdul ^{[1
]}

Volla, Chandra M. R. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Bombay 400076, Maharashtra, India

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2018年 / 24卷 / 11期

关键词：

benzoxazinones; isatoic anhydride; nitrogen; rhodium; triazoles; RHODIUM(II) AZAVINYL CARBENES; H FUNCTIONALIZATION REACTIONS; HUMAN-LEUKOCYTE ELASTASE; TERMINAL ALKYNES; DIASTEREOSELECTIVE SYNTHESIS; CARBONYLATIVE SYNTHESIS; EFFICIENT SYNTHESIS; FACILE SYNTHESIS; SULFONYL AZIDES; TRANSANNULATION;

D O I：

10.1002/chem.201705036

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A convenient and simple, Rh-II-catalyzed denitrogenative method for the synthesis of biologically interesting 2-amino-benzoxazinones and 5-amino-oxadiazoles from readily available isatoic anhydrides and oxadiazolones has been developed. These reactions proceed via an O-H insertion onto alpha-imino Rh-II-carbenoid species followed by a rearrangement. The scope of the reaction can also be extended to benzoxazinones to access amino-substituted benzoxazines.

引用

页码：2558 / 2564

页数：7

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