Similar Long-Term Outcomes in Children Presenting With Abscess vs Phlegmon at Diagnosis of Crohn Disease

被引:0
作者
Fondell, Andrew W. [1 ]
Mosha, Maua H. [1 ]
Maltz, Ross M. [2 ,3 ]
Boyle, Brendan M. [2 ]
Niklinska-Schirtz, Barbara Joanna [4 ]
Kugathasan, Subra [4 ]
Gibson, Meghan E. [5 ]
Shapiro, Jason M. [5 ]
Rosenheck, Sarah M. [6 ,7 ]
Langseder, Annette L. [6 ,7 ]
Kennedy, Mary C. [6 ,7 ]
Rosh, Joel R. [6 ,7 ]
Hyams, Jeffrey S. [1 ]
机构
[1] Connecticut Childrens, Div Digest Dis Hepatol & Nutr, 282 Washington St, Hartford, CT 06106 USA
[2] Nationwide Childrens Hosp, Div Pediat Gastroenterol Hepatol & Nutr, Columbus, OH USA
[3] Nationwide Childrens Hosp, Abigail Wexner Res Inst, Ctr Microbial Pathogenesis, Columbus, OH USA
[4] Childrens Healthcare Atlanta, Div Pediat Gastroenterol Nutr & Liver Dis, Atlanta, GA USA
[5] Hasbro Childrens Hosp, Div Pediat Gastroenterol Nutr & Liver Dis, Providence, RI USA
[6] Goryeb Childrens Hosp Atlantic Hlth, Dept Pediat Gastroenterol, Morristown, NJ USA
[7] Goryeb Childrens Hosp Atlantic Hlth, Dept Clin Dev & Res Affairs, Morristown, NJ USA
关键词
Crohn disease; abscess; children; inflammatory bowel disease; phlegmon; INTRAABDOMINAL ABSCESSES; PEDIATRIC-PATIENTS; MANAGEMENT; DRAINAGE;
D O I
10.1093/crocol/otaa060
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background Limited data are available for long-term outcomes of pediatric patients with abdominal abscess or phlegmon at diagnosis of Crohn disease. Methods We performed a retrospective chart review of such children over a recent 6-year period at 5 pediatric inflammatory bowel diseases. Results Fifty-two patients (mean age 15.9 +/- 1.8 years) were reviewed. Thirty-six had an abscess and 27 (75%) required resectional therapy compared to 16 with phlegmon which 10 (63%) requiring surgery. Overall (37/52) 71% had surgery which was performed within 6 months in 32 (86%). Conclusions A similar high surgical rate exists whether pediatric patients with Crohn disease present with abscess or phlegmon. Lay Summary We found the eventual need for surgery was not different in pediatric patients presenting with phlegmon vs abscess at initial diagnosis of Crohn disease. Anti-tumor necrosis factor therapy is successful in preventing surgery in a small group of these patients.
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页码:1 / 5
页数:5
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