Preventing Bacterial Suicide: A Novel Toxin-Antitoxin Strategy

被引：27
|
作者：
Markovski, Monica [1 ]
Wickner, Sue [1 ]
机构：
[1] NCI, Mol Biol Lab, Bethesda, MD 20892 USA
来源：
MOLECULAR CELL | 2013年 / 52卷 / 05期
关键词：
REPLICATION; SYSTEMS;
D O I：
10.1016/j.molcel.2013.11.018
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue of Molecular Cell, Aarke et al. (2013) identify a toxin-antitoxin system in Caulobacter crescentus that acts by a unique mechanism. The toxin, which blocks DNA replication, is constitutively degraded by CIpXP, and this degradation requires the antitoxin, a CIpXP adaptor.
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页码：611 / 612
页数：2
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