Preventing Bacterial Suicide: A Novel Toxin-Antitoxin Strategy

被引：27
|
作者：
Markovski, Monica [1 ]
Wickner, Sue [1 ]
机构：
[1] NCI, Mol Biol Lab, Bethesda, MD 20892 USA
来源：
MOLECULAR CELL | 2013年 / 52卷 / 05期
关键词：
REPLICATION; SYSTEMS;
D O I：
10.1016/j.molcel.2013.11.018
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue of Molecular Cell, Aarke et al. (2013) identify a toxin-antitoxin system in Caulobacter crescentus that acts by a unique mechanism. The toxin, which blocks DNA replication, is constitutively degraded by CIpXP, and this degradation requires the antitoxin, a CIpXP adaptor.
引用
收藏
页码：611 / 612
页数：2
相关论文
共 50 条
  • [31] Clarifying the Link between Toxin-Antitoxin Modules and Bacterial Persistence
    Ronneau, Severin
    Helaine, Sophie
    JOURNAL OF MOLECULAR BIOLOGY, 2019, 431 (18) : 3462 - 3471
  • [32] Bacterial Genome Editing via a Designed Toxin-Antitoxin Cassette
    Wu, Jie
    Deng, Aihua
    Sun, Qinyun
    Bai, Hua
    Sun, Zhaopeng
    Shang, Xiuling
    Zhang, Yun
    Liu, Qan
    Liang, Yong
    Liu, Shuwen
    Che, Yongsheng
    Wen, Tingyi
    ACS SYNTHETIC BIOLOGY, 2018, 7 (03): : 822 - 831
  • [33] Use of Bacterial Toxin-Antitoxin Systems as Biotechnological Tools in Plants
    Rodamilans, Bernardo
    Cheng, Xiaofei
    Simon-Mateo, Carmen
    Garcia, Juan Antonio
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (19)
  • [34] Minigene as a Novel Regulatory Element in Toxin-Antitoxin Systems
    Kedzierska, Barbara
    Potrykus, Katarzyna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (24)
  • [35] Biochemical and structural analysis of a novel toxin-antitoxin module
    Piscotta, Frank
    Link, A. James
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [36] A Common Origin for the Bacterial Toxin-Antitoxin Systems parD and ccd, Suggested by Analyses of Toxin/Target and Toxin/Antitoxin Interactions
    Smith, Andrew B.
    Lopez-Villarejo, Juan
    Diago-Navarro, Elizabeth
    Mitchenall, Lesley A.
    Barendregt, Arjan
    Heck, Albert J.
    Lemonnier, Marc
    Maxwell, Anthony
    Diaz-Orejas, Ramon
    PLOS ONE, 2012, 7 (09):
  • [37] Bacterial toxin-antitoxin modules: classification, functions, and association with persistence
    Singh, Garima
    Yadav, Mohit
    Ghosh, Chaitali
    Rathore, Jitendra Singh
    CURRENT RESEARCH IN MICROBIAL SCIENCES, 2021, 2
  • [38] TOXIN-ANTITOXIN MODULES AND SYMBIOSIS
    Bodogai, M.
    Ferenczi, Sz.
    Miclea, S. P.
    Papp, P.
    Dusha, I.
    BIOLOGICAL NITROGEN FIXATION: TOWARDS POVERTY ALLEVIATION THROUGH SUSTAINABLE AGRICULTURE, 2008, 42 : 237 - +
  • [39] Frozen toxin-antitoxin reactions
    Kelley, ER
    JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1924, 82 : 567 - 567
  • [40] Toxin-antitoxin Flocculation in a tetanus
    Sulkin, SE
    PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1936, 34 (04): : 555 - 557
12345