Impairments in hearing and vision impact on mortality in older people: the AGES-Reykjavik Study

被引:110
作者
Fisher, Diana [1 ]
Li, Chuan-Ming [2 ]
Chiu, May S. [2 ]
Themann, Christa L. [3 ]
Petersen, Hannes [4 ,5 ]
Jonasson, Frithbert [4 ,6 ]
Jonsson, Palmi V. [4 ,7 ]
Sverrisdottir, Johanna Eyrun [8 ]
Garcia, Melissa [9 ]
Harris, Tamara B. [9 ]
Launer, Lenore J. [9 ]
Eiriksdottir, Gudny [8 ]
Gudnason, Vilmundur [4 ,8 ]
Hoffman, Howard J. [2 ]
Cotch, Mary Frances [1 ]
机构
[1] NEI, Div Epidemiol & Clin Applicat, NIH, Bethesda, MD 20892 USA
[2] NIDCD, Div Sci Programs, Epidemiol & Stat Program, NIH, Bethesda, MD USA
[3] NIOSH, Hearing Loss Prevent Team, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA
[4] Univ Iceland, Fac Med, Reykjavik, Iceland
[5] Landspitali Univ Hosp, Dept Otolaryngol Head & Neck Surg, Reykjavik, Iceland
[6] Landspitali Univ Hosp, Reykjavik, Iceland
[7] Landspitali Univ Hosp, Dept Geriatr, IS-101 Reykjavjk, Iceland
[8] Iceland Heart Assoc, Kopavogur, Iceland
[9] NIA, Lab Epidemiol Demog & Biometry, Intramural Res Program, NIH, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
AGES-Reykjavik study; hearing; vision; dual sensory impairment; all-cause mortality; cardiovascular disease mortality; older people; HEALTH INTERVIEW SURVEY; VISUAL IMPAIRMENT; SENSORY IMPAIRMENT; FOLLOW-UP; POPULATION; DISABILITY; CATARACT; PROJECT; ACUITY; ADULTS;
D O I
10.1093/ageing/aft122
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objective: to examine the relationships between impairments in hearing and vision and mortality from all-causes and cardiovascular disease (CVD) among older people. Design: population-based cohort study. Participants: the study population included 4,926 Icelandic individuals, aged >= 67 years, 43.4% male, who completed vision and hearing examinations between 2002 and 2006 in the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-RS) and were followed prospectively for mortality through 2009. Methods: participants were classified as having 'moderate or greater' degree of impairment for vision only (VI), hearing only (HI), and both vision and hearing (dual sensory impairment, DSI). Cox proportional hazard regression, with age as the time scale, was used to calculate hazard ratios (HR) associated with impairment and mortality due to all-causes and specifically CVD after a median follow-up of 5.3 years. Results: the prevalence of HI, VI and DSI were 25.4, 9.2 and 7.0%, respectively. After adjusting for age, significantly (P < 0.01) increased mortality from all causes, and CVD was observed for HI and DSI, especially among men. After further adjustment for established mortality risk factors, people with HI remained at higher risk for CVD mortality [HR: 1.70 (1.27-2.27)], whereas people with DSI remained at higher risk of all-cause mortality [HR: 1.43 (1.11-1.85)] and CVD mortality [HR: 1.78 (1.18-2.69)]. Mortality rates were significantly higher in men with HI and DSI and were elevated, although not significantly, among women with HI. Conclusions: older men with HI or DSI had a greater risk of dying from any cause and particularly cardiovascular causes within a median 5-year follow-up. Women with hearing impairment had a non-significantly elevated risk. Vision impairment alone was not associated with increased mortality.
引用
收藏
页码:69 / 76
页数:8
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