A plasma cell-based pericardial effusion leading to tamponade in a patient with multiple myeloma - a case report and review of the literature

被引:5
|
作者
Skipina, Travis M. [1 ]
Sane, David C. [2 ]
Cui, Charles [2 ]
Song, Steven [2 ]
Phillips, Stephen G. [2 ]
Jarrett, Robert W. [3 ]
机构
[1] Virginia Tech, Carilion Sch Med, 2 Riverside Circle, Roanoke, VA 24016 USA
[2] Carilion Clin, Dept Med, Div Cardiovasc Dis, Roanoke, VA USA
[3] Domin Pathol Associates, Roanoke, VA USA
关键词
Multiple myeloma; Cardiac tamponade; Pericardial effusion; Plasmacytoma; Plasma cell; CARDIAC-TAMPONADE; EXTRAMEDULLARY MYELOMA; INVOLVEMENT; RELAPSE; MANAGEMENT;
D O I
10.1016/j.carpath.2019.02.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A rare case of extramedullary multiple myeloma causing cardiac tamponade secondary to a plasma cell-based pericardial effusion is described. A systematic search using PubMed (National Library of Medicine) was used to identify a further 27 cases dating back to 1970. Case characteristics, treatment strategies, and survival time following tamponade are discussed. Linear regression demonstrated a weak but statistically significant correlation between survival time following tamponade and treatment with systemic chemotherapy and steroids (beta=16.8 weeks, P=.009). However, this manifestation of extramedullary multiple myeloma still conveys a dismal prognosis with a median survival following tamponade of only 6 weeks based on our review. (C) 2019 Elsevier Inc. All rights reserved.
引用
收藏
页码:41 / 46
页数:6
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