A plasma cell-based pericardial effusion leading to tamponade in a patient with multiple myeloma - a case report and review of the literature

被引：5

作者：

Skipina, Travis M. ^{[1
]}

Sane, David C. ^{[2
]}

Cui, Charles ^{[2
]}

Song, Steven ^{[2
]}

Phillips, Stephen G. ^{[2
]}

Jarrett, Robert W. ^{[3
]}

机构：

[1] Virginia Tech, Carilion Sch Med, 2 Riverside Circle, Roanoke, VA 24016 USA

[2] Carilion Clin, Dept Med, Div Cardiovasc Dis, Roanoke, VA USA

[3] Domin Pathol Associates, Roanoke, VA USA

来源：

CARDIOVASCULAR PATHOLOGY | 2019年 / 40卷

关键词：

Multiple myeloma; Cardiac tamponade; Pericardial effusion; Plasmacytoma; Plasma cell; CARDIAC-TAMPONADE; EXTRAMEDULLARY MYELOMA; INVOLVEMENT; RELAPSE; MANAGEMENT;

D O I：

10.1016/j.carpath.2019.02.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A rare case of extramedullary multiple myeloma causing cardiac tamponade secondary to a plasma cell-based pericardial effusion is described. A systematic search using PubMed (National Library of Medicine) was used to identify a further 27 cases dating back to 1970. Case characteristics, treatment strategies, and survival time following tamponade are discussed. Linear regression demonstrated a weak but statistically significant correlation between survival time following tamponade and treatment with systemic chemotherapy and steroids (beta=16.8 weeks, P=.009). However, this manifestation of extramedullary multiple myeloma still conveys a dismal prognosis with a median survival following tamponade of only 6 weeks based on our review. (C) 2019 Elsevier Inc. All rights reserved.

引用

页码：41 / 46

页数：6

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