Crosstalk Between the SUMO and Ubiquitin Pathways

被引:37
作者
Hunter, T. [1 ]
Sun, H. [1 ]
机构
[1] Salk Inst Biol Studies, Mol & Cell Biol Lab, La Jolla, CA USA
来源
UBIQUITIN SYSTEM IN HEALTH AND DISEASE | 2009年 / 1卷
关键词
REGULATES RECOMBINATIONAL REPAIR; DNA-DAMAGE TOLERANCE; RING FINGER PROTEIN; SACCHAROMYCES-CEREVISIAE; LIGASE ACTIVITY; TRANSCRIPTION FACTOR; SMC5-SMC6; COMPLEX; BINDING MOTIF; RNF4; YEAST;
D O I
10.1007/2789_2008_098
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Several ways in which the SUMO and ubiquitin pathways can intersect and communicate have recently been discovered. This review discusses the principles of crosstalk between SUMOylation and ubiquitination, focusing on the RNF4 family of RING finger E3 ubiquitin ligases, which specifically recognize SUMOylated proteins via their SUMO moiety for ubiquitination.
引用
收藏
页码:1 / 16
页数:16
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