Angiographic Patterns of Restenosis After Sirolimus-Eluting Stent Implantation

被引：14

作者：

Kitahara, Hideki ^{[1
]}

Kobayashi, Yoshio ^{[1
]}

Takebayashi, Hideo ^{[2
]}

Nakamura, Yoshitake ^{[3
]}

Kuroda, Nakabumi ^{[1
]}

Miyazaki, Akira ^{[3
]}

Haruta, Seiichi ^{[2
]}

Komuro, Issei ^{[1
]}

机构：

[1] Chiba Univ, Chuo Ku, Dept Cardiovasc Sci & Med, Grad Sch Med, Chiba 2608677, Japan

[2] Fukuyama Cardiovasc Hosp, Div Cardiol, Fukuyama, Hiroshima, Japan

[3] Chiba Cardiovasc Ctr, Div Cardiol, Ichihara, Chiba, Japan

来源：

CIRCULATION JOURNAL | 2009年 / 73卷 / 03期

关键词：

Angioplasty; Drug-eluting stent; Restenosis; Sirolimus; INTRAVASCULAR ULTRASOUND; CORONARY-ARTERY; JAPANESE PATIENTS; OUTCOMES; POLYMER; IMPACT; FRACTURE; DISEASE; SAFETY; DAMAGE;

D O I：

10.1253/circj.CJ-08-0720

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Large-scale randomized trials demonstrate a high proportion of focal restenosis after drug-eluting stent (DES) implantation. On the other hand, recent reports have shown that in real-world practice a significant proportion of the restenosis is non-focal when DESs are used in unselected lesions. The present study evaluated angiographic patterns of restenosis after sirolimus-eluting stent (SES) implantation in Japan. Methods and Results: Angiographic restenosis patterns of all consecutive restenotic lesions (n=124) after SES implantation were evaluated and classified according to the following scheme: focal (<= 10mm in length), diffuse (restenosis >10mm within the stent), proliferative (restenosis >10mm in length extending outside the stent), and occlusive. There were 98 focal (79.0%), 15 diffuse (12.1%), and 5 proliferative restenoses (4.0%) and 6 total occlusions (4.8%). Focal intrastent restenosis was most dominant (42.7%). Proximal edge restenosis occurred in 22 lesions (17.7%). Multivariate analysis demonstrated diabetes mellitus (P<0.01) as an independent predictor of non-focal restenosis. Conclusions: Focal restenosis is predominant after SES implantation in real-world practice in Japan. (Circ J 2009; 73: 508-511)

引用

页码：508 / 511

页数：4

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