Withanolides with Phytotoxic Activity from Two Species of the Genus Salpichroa: S. origanifolia and S. tristis var. lehmannii

被引:8
|
作者
Nicotra, Viviana E. [1 ]
Basso, Ana V. [1 ]
Ramacciotti, Natalia S. [1 ]
Misico, Rosana I. [2 ,3 ]
机构
[1] Univ Nacl Cordoba, Inst Multidisciplinario Biol Vegetal IMBIV CONICE, Fac Ciencias Quim, RA-5000 Cordoba, Argentina
[2] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Organ, RA-1428 Buenos Aires, DF, Argentina
[3] Univ Buenos Aires, Fac Ciencias Exactas & Nat, UMYMFOR CONICET UBA, Buenos Aires, DF, Argentina
来源
JOURNAL OF NATURAL PRODUCTS | 2013年 / 76卷 / 12期
关键词
NICANDRA-PHYSALOIDES;
D O I
10.1021/np400559p
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Seven new withanolides, salpichrolides O-U (1-7), the known 2,3-dihydrosalpichrolide B (9), a substance not previously isolated from a natural source, and three known compounds, salpichrolide D (8), salpichrolide A (10), and salpichrolide C (11), were isolated and characterized from the aerial parts of Salpichroa origanifolia and S. tristis var. lehmannii. Compounds 1-4 and 8 have an oxygenated D ring, while compounds 5-7 and 9-11 possess a six-membered aromatic D ring. The structures of the isolated compounds were identified by analysis of their spectroscopic data including NMR and MS. Withanolides 1, 3, 8, 10, and 11 exhibited selective radicle growth inhibition toward Lactuca sativa (lettuce) at 150 and 400 ppm.
引用
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页码:2219 / 2225
页数:7
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