Patient preference randomised controlled trials in mental health research

被引：63

作者：

Howard, L ^{[1
]}

Thornicroft, G ^{[1
]}

机构：

[1] Kings Coll London, Inst Psychiat, Hlth Serv Res Dept, London SE5 8AF, England

来源：

BRITISH JOURNAL OF PSYCHIATRY | 2006年 / 188卷

基金：

英国医学研究理事会;

关键词：

D O I：

10.1192/bjp.188.4.303

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The relationship between psychiatric patients' preferences for different treatments and the outcome of interventions is unclear, as the few relevant trials have tended to be underpowered. Strong patient preferences result in patients refusing to enter a trial. This leads to bias and limits generalisability, and the patient preference randomised controlled trial (RCT) design has been proposed as an alternative. Limitations and advantages of patient preference RCTs are discussed.

引用

页码：303 / 304

页数：2

共 13 条

[1]

Bradley C, 1996, LANCET, V347, P1118

[2] PATIENT PREFERENCES AND RANDOMIZED CLINICAL-TRIALS [J].

BREWIN, CR ;

BRADLEY, C .

BRITISH MEDICAL JOURNAL, 1989, 299 (6694) :313-315

[3] What is the prior probability of a proposed new treatment being superior to established treatments? [J].

Chalmers, I .

BRITISH MEDICAL JOURNAL, 1997, 314 (7073) :74-75

[4] Antidepressant drugs and generic counselling for treatment of major depression in primary care: randomised trial with patient preference arms [J].

Chilvers, C ;

Dewey, M ;

Fielding, K ;

Gretton, V ;

Miller, P ;

Palmer, B ;

Weller, D ;

Churchill, R ;

Williams, I ;

Bedi, N ;

Duggan, C ;

Lee, A ;

Harrison, G .

BMJ-BRITISH MEDICAL JOURNAL, 2001, 322 (7289) :772-775

[5] Impact of participant and physician intervention preferences on randomized trials - A systematic review [J].

King, M ;

Nazareth, I ;

Lampe, F ;

Bower, P ;

Chandler, M ;

Morou, M ;

Sibbald, B ;

Lai, R .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 293 (09) :1089-1099

[6] EFFECT OF RANDOM VERSUS NONRANDOM ASSIGNMENT IN A COMPARISON OF INPATIENT AND DAY HOSPITAL REHABILITATION FOR MALE ALCOHOLICS [J].

MCKAY, JR ;

ALTERMAN, AI ;

MCLELLAN, AT ;

SNIDER, EC ;

OBRIEN, CP .

JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1995, 63 (01) :70-78

[7] Randomised controlled trial of exercise for low back pain: clinical outcomes, costs, and preferences [J].

Moffett, JK ;

Torgerson, D ;

Bell-Syer, S ;

Jackson, D ;

Llewlyn-Phillips, H ;

Farrin, A ;

Barber, J .

BRITISH MEDICAL JOURNAL, 1999, 319 (7205) :279-283

[8]

OLSCHEWSKI M, 1985, METHOD INFORM MED, V24, P131

[9]

Schmoor C, 1996, STAT MED, V15, P263, DOI 10.1002/(SICI)1097-0258(19960215)15:3<263::AID-SIM165>3.0.CO

[10]

2-K

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