The Complement System Mediates COVID-19 Endothelial Cell Injury, Modifying Cell Permeability

被引:2
|
作者
Bohorquez, Arlette [1 ]
Rostam, Nlyousha [1 ]
Ortiz-Sandoval, Carolina [1 ]
Howard, Claire [1 ]
Kahr, Walter H. A. [2 ,3 ]
Campbell, Christopher J. [4 ]
Licht, Christoph [2 ,5 ]
机构
[1] Hosp Sick Children, Cell Biol, Toronto, ON, Canada
[2] Hosp Sick Children, Cell Biol Program, Toronto, ON, Canada
[3] Hosp Sick Children, Div Haematol Oncol, Toronto, ON, Canada
[4] Paragon Ventures Inc Res, Vancouver, BC, Canada
[5] Hosp Sick Children, Div Nephrol, Toronto, ON, Canada
关键词
D O I
10.1182/blood-2022-169506
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2665 / 2666
页数:2
相关论文
共 50 条
  • [21] Endothelial Cell Calcium Influx Mediates Trauma-induced Endothelial Permeability
    Schaid Jr, Terry R.
    Mitra, Sanchayita
    Stafford, Preston
    Debot, Margot
    Thielen, Otto
    Hallas, William
    Cralley, Alexis
    Gallagher, Lauren
    Jeffrey, Danielle
    Hansen, Kirk C.
    D'Alessandro, Angelo
    Silliman, Christopher C.
    Dabertrand, Fabrice
    Cohen, Mitchell J.
    ANNALS OF SURGERY, 2025, 281 (04) : 671 - 681
  • [22] Coagulopathy, endothelial dysfunction, thrombotic microangiopathy and complement activation: potential role of complement system inhibition in COVID-19
    Wang, Xin
    Sahu, Kamal Kant
    Cerny, Jan
    JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2021, 51 (03) : 657 - 662
  • [23] Coagulopathy, endothelial dysfunction, thrombotic microangiopathy and complement activation: potential role of complement system inhibition in COVID-19
    Xin Wang
    Kamal Kant Sahu
    Jan Cerny
    Journal of Thrombosis and Thrombolysis, 2021, 51 : 657 - 662
  • [25] Glutamine Deficiency Promotes Immune and Endothelial Cell Dysfunction in COVID-19
    Durante, William
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (08)
  • [26] Endothelial cell biomarkers in critically ill COVID-19 patients with encephalitis
    Altmayer, Victor
    Ziveri, Jason
    Frere, Corinne
    Salem, Joe-Elie
    Weiss, Nicolas
    Cao, Albert
    Marois, Clemence
    Rohaut, Benjamin
    Demeret, Sophie
    Bourdoulous, Sandrine
    Le Guennec, Loic
    JOURNAL OF NEUROCHEMISTRY, 2022, 161 (06) : 492 - 505
  • [27] Complement activation induces excessive T cell cytotoxicity in severe COVID-19
    Georg, Philipp
    Astaburuaga-Garcia, Rosario
    Bonaguro, Lorenzo
    Brumhard, Sophia
    Michalick, Laura
    Lippert, Lena J.
    Kostevc, Tomislav
    Gaebel, Christiane
    Schneider, Maria
    Streitz, Mathias
    Demichev, Vadim
    Gemuend, Ioanna
    Barone, Matthias
    Tober-Lau, Pinkus
    Helbig, Elisa T.
    Hillus, David
    Petrov, Lev
    Stein, Julia
    Dey, Hannah-Philine
    Paclik, Daniela
    Iwert, Christina
    Muelleder, Michael
    Aulakh, Simran Kaur
    Djudjaj, Sonja
    Buelow, Roman D.
    Mei, Henrik E.
    Schulz, Axel R.
    Thiel, Andreas
    Hippenstiel, Stefan
    Saliba, Antoine-Emmanuel
    Eils, Roland
    Lehmann, Irina
    Mall, Marcus A.
    Stricker, Sebastian
    Roehmel, Jobst
    Corman, Victor M.
    Beule, Dieter
    Wyler, Emanuel
    Landthaler, Markus
    Obermayer, Benedikt
    von Stillfried, Saskia
    Boor, Peter
    Demir, Munevver
    Wesselmann, Hans
    Suttorp, Norbert
    Uhrig, Alexander
    Mueller-Redetzky, Holger
    Nattermann, Jacob
    Kuebler, Wolfgang M.
    Meisel, Christian
    CELL, 2022, 185 (03) : 493 - +
  • [28] Endothelial cell infection and dysfunction, immune activation in severe COVID-19
    Qin, Zhongnan
    Liu, Fengming
    Blair, Robert
    Wang, Chenxiao
    Yang, Haoran
    Mudd, Joseph
    Currey, Joshua M.
    Iwanaga, Naoki
    He, Jibao
    Mi, Ren
    Han, Kun
    Midkiff, Cecily C.
    Alam, Mohammad Afaque
    Aktas, Bertal H.
    Vander Heide, Richard S.
    Veazey, Ronald
    Piedimonte, Giovanni
    Maness, Nicholas J.
    Ergun, Suleyman
    Mauvais-Jarvis, Franck
    Rappaport, Jay
    Kolls, Jay K.
    Qin, Xuebin
    THERANOSTICS, 2021, 11 (16): : 8076 - 8091
  • [29] COVID-19 and Cell Stress
    Elfiky, Abdo A.
    Ibrahim, Ibrahim M.
    Amin, Fatma G.
    Ismail, Alaa M.
    Elshemey, Wael M.
    CORONAVIRUS DISEASE - COVID-19, 2021, 1318 : 169 - 178
  • [30] Circulating Endothelial Cells as a Marker of Endothelial Injury in Severe COVID-19
    Guervilly, Christophe
    Burtey, Stephane
    Sabatier, Florence
    Cauchois, Raphael
    Lano, Guillaume
    Abdili, Evelyne
    Daviet, Florence
    Arnaud, Laurent
    Brunet, Philippe
    Hraiech, Sami
    Jourde-Chiche, Noemie
    Koubi, Marie
    Lacroix, Romaric
    Pietri, Lea
    Berda, Yael
    Robert, Thomas
    Degioanni, Clara
    Velier, Melanie
    Papazian, Laurent
    Kaplanski, Gilles
    Dignat-George, Francoise
    JOURNAL OF INFECTIOUS DISEASES, 2020, 222 (11): : 1789 - 1793