Maternal Obesity and Pre-Pregnancy Folic Acid Supplementation

被引：21

作者：

Farah, Nadine ^{[1
]}

Kennedy, Cormac ^{[1
]}

Turner, Ciara ^{[1
]}

O'Dwyer, Vicky ^{[1
]}

Kennelly, Mairead M. ^{[1
]}

Turner, Michael J. ^{[1
]}

机构：

[1] Coombe Women & Infants Univ Hosp, UCD Ctr Human Reprod, Dublin 8, Ireland

来源：

OBESITY FACTS | 2013年 / 6卷 / 02期

关键词：

Maternal obesity; Pre-pregnancy folic acid; Body mass index; Unplanned pregnancy; NEURAL-TUBE DEFECTS; ORAL-CONTRACEPTIVE FAILURE; BODY-MASS INDEX; UNITED-STATES; SPINA-BIFIDA; WEIGHT; RISK; PREGNANCY; PREVALENCE;

D O I：

10.1159/000350393

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: The purpose of this nested cohort study was to compare the rate of pre-pregnancy supplementation in obese women with that of women with a normal BMI. Methods: Pregnant women were enrolled at their convenience in a large university hospital. Weight and height were measured in the first trimester and BMI categorised. Results: Of the 288 women, 35.1% were in the normal, 29.5% in the overweight and 35.4% in the obese BMI categories. Only 45.1% (n = 46) of the obese women took pre-pregnancy folic acid compared with 60.4% (n = 61) of women with a normal BMI (p < 0.03). The lower incidence of folic acid supplementation in obese women was associated with an unplanned pregnancy in 36.3% of women compared with 22.8% in the normal BMI category (p < 0.04). Conclusions: Obese women should take folate supplements whether they are planning to conceive or not. Copyright (C) 2013 S. Karger GmbH, Freiburg

引用

页码：211 / 215

页数：5

共 23 条

[1] Maternal obesity, gestational diabetes, and central nervous system birth defects [J].

Anderson, JL ;

Waller, DK ;

Canfield, MA ;

Shaw, GM ;

Watkins, ML ;

Werler, MM .

EPIDEMIOLOGY, 2005, 16 (01) :87-92

[2]

[Anonymous], COCHRANE DATABASE SY

[3]

Barry S, 2009, Ir Med J, V102, P5

[4] Trends in the postfortification prevalence of spina bifida and anencephaly in the United States [J].

Boulet, Sheree L. ;

Yang, Quanhe ;

Mai, Cara ;

Kirby, Russell S. ;

Collins, Julianne S. ;

Robbins, James M. ;

Meyer, Robert ;

Canfield, Mark A. ;

Mulinare, Joe .

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 2008, 82 (07) :527-532

[5] Association between efficacy and body weight or body mass index for two low-dose oral contraceptives [J].

Burkman, Ronald T. ;

Fisher, Alan C. ;

Wan, George J. ;

Bamowski, Christopher E. ;

LaGuardia, Katherine D. .

CONTRACEPTION, 2009, 79 (06) :424-427

[6]

Centre for Maternal and Child Enquires and Royal College of Obstetricians and Gynaecologists Joint Guideline, 2010, CTR MAT CHILD ENQ RO

[7] Impact of obesity on oral contraceptive pharmacokinetics and hypothalamic-pituitary-ovarian activity [J].

Edelman, Alison B. ;

Carlson, Nichole E. ;

Cherala, Ganesh ;

Munar, Myrna Y. ;

Stouffer, Richard L. ;

Cameron, Judy L. ;

Stanczyk, Frank Z. ;

Jensen, Jeffrey T. .

CONTRACEPTION, 2009, 80 (02) :119-127

[8] Maternal weight and body composition in the first trimester of pregnancy [J].

Fattah, Chro ;

Farah, Nadine ;

Barry, Sinead C. ;

O'Connor, Norah ;

Stuart, Bernard ;

Turner, Michael J. .

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2010, 89 (07) :952-955

[9] Body Mass Index (BMI) in women booking for antenatal care: Comparison between selfreported and digital measurements [J].

Fattah, Chro ;

Farah, Nadine ;

O'Toole, Fiona ;

Barry, Sinead ;

Stuart, Bernard ;

Turner, Michael J. .

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2009, 144 (01) :32-34

[10] Disparities in rates of unintended pregnancy in the United States, 1994 and 2001 [J].

Finer, Larence B. ;

Henshaw, Stanley K. .

PERSPECTIVES ON SEXUAL AND REPRODUCTIVE HEALTH, 2006, 38 (02) :90-96

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