Evaluation of wound healing for hydrogel containing chitosan

被引:0
作者
Lee, Tae-Wan [2 ]
Khang, Gilson [1 ]
Hwang, Sung-Joo [3 ]
Lee, Han-Koo [2 ]
机构
[1] Chonbuk Natl Univ, Polymer BIN Fus Res Team BK21, Jeonju 561756, South Korea
[2] Dae Hwa Pharmaceut Co Ltd, R&D Ctr, Hwasung 445996, Kyunggi, South Korea
[3] Chungnam Natl Univ, Dept Pharm, Taejon 305764, South Korea
关键词
hydrogel; polyurethane foam; wound healing; micro-pig;
D O I
暂无
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Hydrogel dressings of the three dimensional structure containing chitosans and moisturizers were prepared as the treatment of wound. In this study, swelling ratio were compared hydrogel dressings with polyurethane foam dressing to predict the absorptivity of an exudate. and wound healing effect were estimated for 5 weeks by 3 days after inducing the wound on the back of the micro-pig. The swelling ratios of hydrogel dressings and polyurethane foam dressing were indicated 6.04 +/- 0.33 and 5.77 +/- 0.25, respectively. Also, the wound healing effects of hydrogel dressings and polyurethane foam dressing were measured 7.79 +/- 1.48% and 8.22 +/- 3.33%. The wound healing effects of hydrogel dressings and polyurethane foam dressing were showed a lot of similarity, Thus, the hydrogel dressings in this study would be pharmaceutically applicable for the wound healing.
引用
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页码:73 / 78
页数:6
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