Role of developmental overnutrition in pediatric obesity and type 2 diabetes

被引：42

作者：

Dabelea, Dana ^{[1
]}

Harrod, Curtis S. ^{[1
]}

机构：

[1] Univ Colorado Denver, Colorado Sch Publ Hlth, Dept Epidemiol, Aurora, CO 80045 USA

来源：

NUTRITION REVIEWS | 2013年 / 71卷

关键词：

childhood obesity; developmental overnutrition; pediatrics; type; 2; diabetes; BODY-MASS INDEX; GESTATIONAL WEIGHT-GAIN; BIRTH-WEIGHT; OFFSPRING OBESITY; FAT DISTRIBUTION; INCREASING PREVALENCE; INTRAUTERINE EXPOSURE; CHILDHOOD OBESITY; MATERNAL OBESITY; IN-UTERO;

D O I：

10.1111/nure.12061

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Childhood obesity continues to be a significant public health burden. Empirical evidence has begun to identify intrauterine and postnatal pathways that increase the likelihood of excess adiposity and increased risk of type 2 diabetes among offspring. Reviewed here is the evidence supporting a transgenerational vicious cycle that increases obesity and diabetes in offspring and contributes substantially to the increases in obesity and type 2 diabetes observed over the past several decades. The public health impact of these findings is discussed and future research opportunities are outlined. (C) 2013 International Life Sciences Institute

引用

页码：S62 / S67

页数：6

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